Placental MRI: developing accurate quantitative measures of oxygenation

EA Turk, JN Stout, C Ha, J Luo, B Gagoski… - Topics in Magnetic …, 2019 - journals.lww.com
Abstract The Human Placenta Project has focused attention on the need for noninvasive
magnetic resonance imaging (MRI)-based techniques to diagnose and monitor placental …

Normal human and sheep fetal vessel oxygen saturations by T2 magnetic resonance imaging

BS Saini, JRT Darby, S Portnoy, L Sun… - The Journal of …, 2020 - Wiley Online Library
Key points Human fetal Doppler ultrasound and invasive blood gas measurements obtained
by cordocentesis or at the time of delivery reveal similarities with sheep (an extensively used …

Quantification of whole‐organ individual and bilateral renal metabolic rate of oxygen

RS Deshpande, MC Langham, H Lee… - Magnetic …, 2024 - Wiley Online Library
Purpose Renal metabolic rate of oxygen (rMRO2) is a potentially important biomarker of
kidney function. The key parameters for rMRO2 quantification include blood flow rate (BFR) …

MRI‐based quantification of whole‐organ renal metabolic rate of oxygen

RS Deshpande, MC Langham, K Susztak… - NMR in …, 2024 - Wiley Online Library
During the early stages of diabetes, kidney oxygen utilization increases. The mismatch
between oxygen demand and supply contributes to tissue hypoxia, a key driver of chronic …

Interleaved quantitative BOLD: combining extravascular R2ʹ-and intravascular R2-measurements for estimation of deoxygenated blood volume and hemoglobin …

H Lee, EK Englund, FW Wehrli - Neuroimage, 2018 - Elsevier
Quantitative BOLD (qBOLD), a non-invasive MRI method for assessment of hemodynamic
and metabolic properties of the brain in the baseline state, provides spatial maps of …

Factors affecting performance of fetal blood T2 measurements for noninvasive estimation of oxygen saturation

E Hedström, M Piek… - Magnetic …, 2023 - Wiley Online Library
Purpose To ultimately make accurate and precise fetal noninvasive oxygen saturation (sO2)
measurements by T2‐prepared bSSFP more widely available by systematically assessing …

MRI quantification of human fetal O2 delivery rate in the second and third trimesters of pregnancy

AE Rodríguez‐Soto, MC Langham… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose The purpose of this study was to estimate fetal O2 delivery rate in vivo across a
range of gestational ages. Toward this, a calibration equation for T2‐based oximetry was …

Venous cerebral blood volume mapping in the whole brain using venous‐spin‐labeled 3D turbo spin echo

H Lee, FW Wehrli - Magnetic Resonance in Medicine, 2020 - Wiley Online Library
Purpose Venous cerebral blood volume (CBVv) is a major contributor to BOLD contrast, and
therefore is an important parameter for understanding the underlying mechanism. Here, we …

Quantitative T1 and T2 mapping by magnetic resonance fingerprinting (MRF) of the placenta before and after maternal hyperoxia

JN Stout, C Liao, B Gagoski, EA Turk, HA Feldman… - Placenta, 2021 - Elsevier
Introduction MR relaxometry has been used to assess placental exchange function, but
methods to date are not sufficiently fast to be robust to placental motion. Magnetic resonance …

[HTML][HTML] Visualization of cerebrospinal fluid outflow and egress along the nerve roots of the lumbar spine

D Vucevic, V Malis, WC Bae, H Ota, K Oshio… - Bioengineering, 2024 - mdpi.com
Intrinsic cerebrospinal fluid (CSF) dynamics in the brain have been extensively studied,
particularly the egress sites of tagged intrinsic CSF in the meninges. Although spinal CSF …