New insights into protein–polysaccharide complex coacervation: Dynamics, molecular parameters, and applications

J Zheng, P Van der Meeren, W Sun - Aggregate, 2024 - Wiley Online Library
For more than a decade, the discovery of liquid–liquid phase separation within living
organisms has prompted colloid scientists to understand the connection between …

Applications and advancements of polysaccharide-based nanostructures for enhanced drug delivery

AF Kareemi, S Likhitkar - Colloids and Surfaces B: Biointerfaces, 2024 - Elsevier
Growing demand for highly effective, site-specific delivery of pharmaceuticals and
nutraceuticals using nano-sized carriers has prompted increased scrutiny of carrier …

Hydrophobically modified complex coacervates for designing aqueous pressure-sensitive adhesives

L van Westerveld, JE Sayed, M de Graaf, AH Hofman… - Soft Matter, 2023 - pubs.rsc.org
The rheology of complex coacervates can be elegantly tuned via the design and control of
specific non-covalent hydrophobic interactions between the complexed polymer chains. The …

Multi-crosslinked hydrogel built with hyaluronic acid-tyramine, thiolated glycol chitosan and copper-doped bioglass nanoparticles for expediting wound healing

Y Yu, C Wang, Q Fu, Y Wan, A Yu - Carbohydrate Polymers, 2024 - Elsevier
The migration of fibroblasts and endothelial cells is a critical determinant of wound-healing
outcomes for skin injuries. Here, hyaluronic acid-tyramine (HAT) and thiolated glycol …

Effect of chitosan molecular weight and protein to polysaccharide ratio on the rheological and physicochemical properties of milk proteins–chitosan complex …

E Hassanvand, SMA Razavi - International Journal of Biological …, 2024 - Elsevier
The small amplitude oscillatory shear (SAOS) rheological properties of complex coacervate
of milk proteins with high (HMC), medium (MMC), and low (LMC) molecular weight chitosan …

Effect of Polyelectrolyte Charge Density on the Linear Viscoelastic Behavior and Processing of Complex Coacervate Adhesives

L van Westerveld, T Pelras, AH Hofman, K Loos… - …, 2024 - ACS Publications
It is well-known that the phase behavior and physicochemical and adhesive properties of
complex coacervates are readily tuneable with the salt concentration of the medium. For …

[HTML][HTML] Tuning the underwater adhesiveness of antibacterial polysaccharides complex coacervates

P Galland, MH Iqbal, D Favier, M Legros… - Journal of Colloid and …, 2024 - Elsevier
Hypothesis Adjusting the water content and mechanical properties of polyelectrolyte
coacervates for optimal underwater adhesion requires simultaneous control of the …

Decoupling the Effects of Charge Density and Hydrophobicity on the Phase Behavior and Viscoelasticity of Complex Coacervates

IA Ramírez Marrero, L Boudreau, W Hu… - …, 2024 - ACS Publications
Here, we explore the effect of copolymer chemistry on the phase behavior and viscoelasticity
of complex coacervates. To this end, we utilized a library of methacrylate copolymers with …

[HTML][HTML] Stretchable hydrogels of chitosan/hyaluronic acid induced by polyelectrolyte complexation around neutral pH

M Balima, I Morfin, G Sudre, A Montembault - Carbohydrate Polymers, 2024 - Elsevier
In this work, we propose the formation of stretchable hydrogels at neutral pH from the
physical crosslinking of chitosan (CS) and hyaluronic acid (HA) by polyelectrolyte …

Sticky Science: Using Complex Coacervate Adhesives for Biomedical Applications

AN Kwant, JS Es Sayed, M Kamperman… - Advanced …, 2025 - Wiley Online Library
Tissue adhesives are used for various medical applications, including wound closure,
bleeding control, and bone healing. Currently available options often show weak adhesion …