Medicinal mushrooms have important health benefits and exhibit a broad spectrum of
pharmacological activities, including antiallergic, antibacterial, antifungal, anti-inflammatory …

Ethnopharmacological relevance Mushrooms in the genus Hericium are used as functional
food and traditional medicines for a long history in East Asian countries such as China …

Hericium erinaceus is a valuable mushroom known for its strong bioactive properties. It
shows promising potential as an excellent neuroprotective agent, capable of stimulating …

Background: Given the bioactive properties and limited work to date, Hericium erinaceus
(Lion's mane) shows promise in improving cognitive function and mood. However, much of …

Traumatic brain injury (TBI) is a major health and socioeconomic problem affecting the
world. This condition results from the application of external physical force to the brain which …

Background Alzheimer's disease (AD) is a significant cause of dementia demonstrated by
severe and progressive cognitive impairment. While the deposition of amyloid beta (Aβ) …

The presence of a fused 5/6/7 tricyclic core characterizes the group of cyathane diterpene
natural products, that include more than 170 compounds, isolated from fungi such as …

Background: A growing body of research suggests that oxidative stress and
neuroinflammation are early pathogenic features of neurodegenerative disorders. In recent …

The variety of drugs available to treat neurodegenerative diseases is limited. Most of these
drug's efficacy is restricted by individual genetics and disease stages and usually do not …

Introduction Heme oxygenase-1 (HO-1) is a stress-inducible heat shock protein (HSP32)
that exerts cytoprotective effects against oxidative stress and inflammation, and is involved in …