SimVascular: an open source pipeline for cardiovascular simulation

A Updegrove, NM Wilson, J Merkow, H Lan… - Annals of biomedical …, 2017 - Springer
Patient-specific cardiovascular simulation has become a paradigm in cardiovascular
research and is emerging as a powerful tool in basic, translational and clinical research. In …

Computational fluid dynamics modeling of hemodynamic parameters in the human diseased aorta: A systematic review

CW Ong, I Wee, N Syn, S Ng, HL Leo… - Annals of Vascular …, 2020 - Elsevier
Background The analysis of the correlation between blood flow and aortic pathology through
computational fluid dynamics (CFD) shows promise in predicting disease progression, the …

[HTML][HTML] Tumor vessel normalization after aerobic exercise enhances chemotherapeutic efficacy

KL Schadler, NJ Thomas, PA Galie, DH Bhang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Targeted therapies aimed at tumor vasculature are utilized in combination with
chemotherapy to improve drug delivery and efficacy after tumor vascular normalization …

A haemodynamic predictor of intraluminal thrombus formation in abdominal aortic aneurysms

P Di Achille, G Tellides… - Proceedings of the …, 2014 - royalsocietypublishing.org
Intraluminal thrombus (ILT) is present in over 75% of all abdominal aortic aneurysms (AAAs)
and probably contributes to the complex biomechanics and pathobiology of these lesions. A …

A longitudinal comparison of hemodynamics and intraluminal thrombus deposition in abdominal aortic aneurysms

A Arzani, GY Suh, RL Dalman… - American Journal of …, 2014 - journals.physiology.org
Abdominal aortic aneurysm (AAA) is often accompanied by in traluminal thrombus (ILT),
which complicates AAA progression and risk of rupture. Patient-specific computational fluid …

Lagrangian postprocessing of computational hemodynamics

SC Shadden, A Arzani - Annals of biomedical engineering, 2015 - Springer
Recent advances in imaging, modeling, and computing have rapidly expanded our
capabilities to model hemodynamics in the large vessels (heart, arteries, and veins). This …

Exercise modulation of tumour perfusion and hypoxia to improve radiotherapy response in prostate cancer

O Schumacher, DA Galvao, DR Taaffe… - Prostate Cancer and …, 2021 - nature.com
Background An increasing number of studies indicate that exercise plays an important role
in the overall care of prostate cancer (PCa) patients before, during and after treatment …

Lagrangian wall shear stress structures and near-wall transport in high-Schmidt-number aneurysmal flows

A Arzani, AM Gambaruto, G Chen… - Journal of Fluid …, 2016 - cambridge.org
The wall shear stress (WSS) vector field provides a signature for near-wall convective
transport, and can be scaled to obtain a first-order approximation of the near-wall fluid …

Abnormal flow dynamics result in low wall shear stress and high oscillatory shear index in abdominal aortic dilatation: initial in vivo assessment with 4D-flow MRI

Y Takehara, H Isoda, M Takahashi, N Unno… - … Resonance in Medical …, 2020 - jstage.jst.go.jp
Purpose: To characterize the non-laminar flow dynamics and resultant decreased wall shear
stress (WSS) and high oscillatory shear index (OSI) of the infrarenal abdominal aortic …

Characterization of the transport topology in patient-specific abdominal aortic aneurysm models

A Arzani, SC Shadden - Physics of Fluids, 2012 - pubs.aip.org
Abdominal aortic aneurysm (AAA) is characterized by disturbed blood flow patterns that are
hypothesized to contribute to disease progression. The transport topology in six patient …