The antioxidant potential of vitamins and their implication in metabolic abnormalities

P Theodosis-Nobelos, EA Rekka - Nutrients, 2024 - mdpi.com
Vitamins are micronutrients necessary for the normal function of the body. Although each
vitamin has different physicochemical properties and a specific role in maintaining life, they …

The beneficial role of vitamin D in obesity: possible genetic and cell signaling mechanisms

K vinh quốc Lương, LTH Nguyễn - Nutrition journal, 2013 - Springer
The prevalence rates of overweight and obesity are considered an important public issue in
the United States, and both of these conditions are increasing among both children and …

Myricetin protects cells against oxidative stress-induced apoptosis via regulation of PI3K/Akt and MAPK signaling pathways

KA Kang, ZH Wang, R Zhang, MJ Piao, KC Kim… - International journal of …, 2010 - mdpi.com
Recently, we demonstrated that myricetin exhibits cytoprotective effects against H2O2-
induced cell damage via its antioxidant properties. In the present study, myricetin was found …

Ascorbate prevents cell death from prolonged exposure to glutamate in an in vitro model of human dopaminergic neurons

S Ballaz, I Morales, M Rodríguez… - Journal of …, 2013 - Wiley Online Library
Ascorbate (vitamin C) is a nonenzymatic antioxidant highly concentrated in the brain. In
addition to mediating redox balance, ascorbate is linked to glutamate neurotransmission in …

Neuroprotection by co-treatment and post-treating with calcitriol following the ischemic and excitotoxic insult in vivo and in vitro

M Kajta, D Makarewicz, E Ziemińska, D Jantas… - Neurochemistry …, 2009 - Elsevier
Several in vivo and in vitro studies have demonstrated the neuroprotective potential of
pretreatment with 1α, 25-dihydroxyvitamin D3 (calcitriol). The aim of the present study was to …

Protective effects of 1α,25‐Dihydroxyvitamin D3 on cultured neural cells exposed to catalytic iron

F Uberti, V Morsanuto, C Bardelli… - Physiological …, 2016 - Wiley Online Library
Recent studies have postulated a role for vitamin D and its receptor on cerebral function,
and anti‐inflammatory, immunomodulatory and neuroprotective effects have been …

Roles of vitamin D in amyotrophic lateral sclerosis: possible genetic and cellular signaling mechanisms

K Lương, LTH Nguyễn - Molecular Brain, 2013 - Springer
Evidence suggests that there are aberrations in the vitamin D-endocrine system in subjects
with amyotrophic lateral sclerosis (ALS). Here, we review the relationship between vitamin D …

Combination of an insulin and a GLP-1-agonist

U Werner, B Rotthauser - US Patent 9,526,764, 2016 - Google Patents
US9526764B2 - Combination of an insulin and a GLP-1-agonist - Google Patents
US9526764B2 - Combination of an insulin and a GLP-1-agonist - Google Patents Combination …

Calcitriol increases frataxin levels and restores mitochondrial function in cell models of Friedreich Ataxia

E Britti, F Delaspre, A Sanz-Alcázar… - Biochemical …, 2021 - portlandpress.com
Friedreich ataxia (FA) is a neurodegenerative disease caused by the deficiency of frataxin, a
mitochondrial protein. In primary cultures of dorsal root ganglia neurons, we showed that …

The rationale for deltanoids in therapy for myeloid leukemia: Role of KSR–MAPK–C/EBP pathway

GP Studzinski, X Wang, Y Ji, Q Wang, Y Zhang… - The Journal of steroid …, 2005 - Elsevier
The evidence for the promising potential for derivatives of Vitamin D (deltanoids) in the
treatment of myeloid leukemias is increasing, but currently is not matched by the …