The heart is uniquely responsible for providing its own blood supply through the coronary
circulation. Regulation of coronary blood flow is quite complex and, after over 100 years of …

▪ Abstract We review major experimental and theoretical studies on microcirculation and
hemorheology, focusing on mechanics of blood flow and the vascular wall. We discuss flow …

Background Zero-dimensional (lumped parameter) and one dimensional models, based on
simplified representations of the components of the cardiovascular system, can contribute …

With advances in technology, the physiological assessment of coronary artery disease in
patients in the catheterization laboratory has become increasingly important in both clinical …

The cardiac muscle and the coronary vasculature are in close proximity to each other, and a
two-way interaction, called cross-talk, exists. Here we focus on the mechanical aspects of …

Objective—The role of fluid shear stress (FSS) in collateral vessel growth remains disputed
and prospective in vivo experiments to test its morphogenic power are rare. Therefore, we …

Known as the bible of biomedical engineering, The Biomedical Engineering Handbook,
Fourth Edition, sets the standard against which all other references of this nature are …

The relationships between blood flow, mechanotransduction, and the localization of arterial
lesions can now be advanced by the incorporation of new technologies and the refinement …

The autoregulation of blood flow, the maintenance of almost constant blood flow in the face
of variations in arterial pressure, is characteristic of many tissue types. Here, contributions to …

Relative to normal tissues, tumor microcirculation exhibits high structural and functional
heterogeneity leading to hypoxic regions and impairing treatment efficacy. Here …