Controlled microwave heating in modern organic synthesis

CO Kappe - Angewandte Chemie International Edition, 2004 - Wiley Online Library
Although fire is now rarely used in synthetic chemistry, it was not until Robert Bunsen
invented the burner in 1855 that the energy from this heat source could be applied to a …

Microwave-assisted synthesis in water as solvent

D Dallinger, CO Kappe - Chemical reviews, 2007 - ACS Publications
Within the past decade, green chemistry has attained the status of a major scientific
discipline. 1, 2 The investigation and application of green chemistry principles has led to the …

[图书][B] Microwaves in organic and medicinal chemistry

CO Kappe, A Stadler, D Dallinger - 2012 - books.google.com
Tailored to the needs of medicinal and natural products chemists, the second edition of this
unique handbook brings the contents up to speed, almost doubling the amount of chemical …

[HTML][HTML] Microwave reactors: A brief review on its fundamental aspects and applications

KK Rana, S Rana - Open Access Library Journal, 2014 - scirp.org
Improved laboratory protocols for convenient and rapid transformations are highly desired in
modern synthetic chemistry. Microwave irradiated reactions have received considerable …

The impact of microwave synthesis on drug discovery

CO Kappe, D Dallinger - Nature Reviews Drug Discovery, 2006 - nature.com
In the past few years, using microwave energy to heat and drive chemical reactions has
become increasingly popular in the medicinal chemistry community. First described 20 years …

Toward rapid,“green”, predictable microwave-assisted synthesis

BA Roberts, CR Strauss - Accounts of Chemical Research, 2005 - ACS Publications
Continuous and batch microwave reactors were constructed for efficient,“green” synthesis
with low-boiling solvents at high temperature in closed vessels. Capabilities for rapid …

Microwave enhanced synthesis

S Caddick, R Fitzmaurice - Tetrahedron, 2009 - Elsevier
Microwave technology has become very important in synthesis and it is reasonable to assert
that there are now very few areas of synthetic organic chemistry that have not been shown to …

[PDF][PDF] Non-conventional methodologies for transition-metal catalysed carbon–carbon coupling: A critical overview. Part 1: The Heck reaction

F Alonso, IP Beletskaya, M Yus - Tetrahedron, 2005 - uwindsor.ca
Abbreviations: A, ampere; AAEMA, deprotonated form of 2-(acetoacetoxy) ethyl
methacrylate; acac, acetylacetonate; Ad, adamantyl; A336, tricaprylmethylammonium …

Multicomponent reactions as a potent tool for the synthesis of benzodiazepines

H Farhid, V Khodkari, MT Nazeri… - Organic & …, 2021 - pubs.rsc.org
Benzodiazepines (BZDs), a diverse class of benzofused seven-membered N-heterocycles,
display essential pharmacological properties and play vital roles in some biochemical …

[图书][B] Microwave heating as a tool for sustainable chemistry

NE Leadbeater - 2010 - taylorfrancis.com
Shorter reaction times, higher product yields, and enhanced selectivity are some of the
advantages microwave heating has over conventional methods, causing its use to transition …