In August 2022, these guidelines were reviewed by an expert work group convened by ASH.
Review included limited searches for new evidence and discussion of the search results …

D-dimer is a soluble fibrin degradation product that results from ordered breakdown of
thrombi by the fibrinolytic system. Numerous studies have shown that D-dimer serves as a …

2.1. 1. Epidemiology and burden of the disease. The annual incidence of first episode of
symptomatic DVT in the adult population ranges from 50 to 100 per 100 000 population, with …

Deep vein thrombosis and pulmonary embolism, collectively referred to as venous
thromboembolism, constitute a major global burden of disease. The diagnostic work-up of …

Importance Venous thromboembolism (VTE), comprising deep vein thrombosis (DVT) and
pulmonary embolism (PE), is a common and potentially fatal disease. Objective To …

Thrombophilia Testing and Venous Thrombosis | New England Journal of Medicine Skip to
main content Access provided by Charite - Universitaetsmedizin Berlin The New England …

Pulmonary embolism is a common and potentially fatal cardiovascular disorder that must be
promptly diagnosed and treated. The diagnosis, risk assessment, and management of …

This guidance document focuses on the diagnosis and treatment of venous
thromboembolism (VTE). Efficient, cost effective diagnosis of VTE is facilitated by combining …

Thrombophilias are hereditary and/or acquired conditions that predispose patients to
thrombosis. Testing for thrombophilia is commonly performed in patients with venous …

D‐dimer assays are commonly used in clinical practice to exclude a diagnosis of deep vein
thrombosis or pulmonary embolism. More recently, they have been also been used to guide …