[HTML][HTML] Behaviorally consequential astrocytic regulation of neural circuits

J Nagai, X Yu, T Papouin, E Cheong, MR Freeman… - Neuron, 2021 - cell.com
Astrocytes are a large and diverse population of morphologically complex cells that exist
throughout nervous systems of multiple species. Progress over the last two decades has …

Glia Development and Function in the Nematode Caenorhabditis elegans

A Singhvi, S Shaham, G Rapti - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
The nematode Caenorhabditis elegans is a powerful experimental setting for uncovering
fundamental tenets of nervous system organization and function. Its nearly invariant and …

How Caenorhabditis elegans Senses Mechanical Stress, Temperature, and Other Physical Stimuli

MB Goodman, P Sengupta - Genetics, 2019 - academic.oup.com
Caenorhabditis elegans lives in a complex habitat in which they routinely experience large
fluctuations in temperature, and encounter physical obstacles that vary in size and …

Ratiometric Matryoshka biosensors from a nested cassette of green-and orange-emitting fluorescent proteins

C Ast, J Foret, LM Oltrogge, R De Michele… - Nature …, 2017 - nature.com
Sensitivity, dynamic and detection range as well as exclusion of expression and
instrumental artifacts are critical for the quantitation of data obtained with fluorescent protein …

Glia-Neuron Interactions in Caenorhabditis elegans

A Singhvi, S Shaham - Annual review of neuroscience, 2019 - annualreviews.org
Glia are abundant components of animal nervous systems. Recognized 170 years ago,
concerted attempts to understand these cells began only recently. From these investigations …

Sensory glia detect repulsive odorants and drive olfactory adaptation

D Duan, H Zhang, X Yue, Y Fan, Y Xue, J Shao, G Ding… - Neuron, 2020 - cell.com
Glia are typically considered as supporting cells for neural development and synaptic
transmission. Here, we report an active role of a glia in olfactory transduction. As a …

A glial ClC Cl− channel mediates nose touch responses in C. elegans

J Fernandez-Abascal, CK Johnson, B Graziano… - Neuron, 2022 - cell.com
In touch receptors, glia and accessory cells play a key role in mechanosensation. However,
the mechanisms underlying such regulation are poorly understood. We show, for the first …

[HTML][HTML] Neuron cilia restrain glial KCC-3 to a microdomain to regulate multisensory processing

S Ray, P Gurung, RS Manning, AA Kravchuk, A Singhvi - Cell Reports, 2024 - cell.com
Glia interact with multiple neurons, but it is unclear whether their interactions with each
neuron are different. Our interrogation at single-cell resolution reveals that a single glial cell …

Cell-type-specific promoters for C. elegans glia

W Fung, L Wexler, MG Heiman - Journal of neurogenetics, 2020 - Taylor & Francis
Glia shape the development and function of the C. elegans nervous system, especially its
sense organs and central neuropil (nerve ring). Cell-type-specific promoters allow …

Shear stress sensing in C. elegans

Z Zhang, X Li, C Wang, F Zhang, J Liu, XZS Xu - Current Biology, 2024 - cell.com
Shear stress sensing represents a vital mode of mechanosensation. 1 Previous efforts have
mainly focused on characterizing how various cell types—for example, vascular endothelial …