Synthetic nanoparticles for vaccines and immunotherapy

DJ Irvine, MC Hanson, K Rakhra, T Tokatlian - Chemical reviews, 2015 - ACS Publications
The immune system plays a critical role in our health. No other component of human
physiology plays a decisive role in as diverse an array of maladies, from deadly diseases …

Advanced nanomedicines for the treatment of inflammatory diseases

R Brusini, M Varna, P Couvreur - Advanced drug delivery reviews, 2020 - Elsevier
Inflammation, a common feature of many diseases, is an essential immune response that
enables survival and maintains tissue homeostasis. However, in some conditions, the …

Reprogramming mitochondrial metabolism in synovial macrophages of early osteoarthritis by a camouflaged meta‐defensome

L Zhang, X Chen, P Cai, H Sun, S Shen… - Advanced …, 2022 - Wiley Online Library
Osteoarthritis (OA) is a low‐grade inflammatory and progressive joint disease, and its
progression is closely associated with an imbalance in M1/M2 synovial macrophages …

Tailoring porous silicon for biomedical applications: from drug delivery to cancer immunotherapy

W Li, Z Liu, F Fontana, Y Ding, D Liu… - Advanced …, 2018 - Wiley Online Library
In the past two decades, porous silicon (PSi) has attracted increasing attention for its
potential biomedical applications. With its controllable geometry, tunable nanoporous …

[HTML][HTML] Current research trends of nanomedicines

Q Liu, J Zou, Z Chen, W He, W Wu - Acta Pharmaceutica Sinica B, 2023 - Elsevier
Owing to the inherent shortcomings of traditional therapeutic drugs in terms of inadequate
therapeutic efficacy and toxicity in clinical treatment, nanomedicine designs have received …

Nanotherapeutics relieve rheumatoid arthritis

M Yang, X Feng, J Ding, F Chang, X Chen - Journal of Controlled Release, 2017 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease associated with
persistent multiarticular synovitis, cartilage destruction, and even loss of joint function …

The solid progress of nanomedicine

JP Martins, J Das Neves, M de la Fuente… - Drug delivery and …, 2020 - Springer
This commentary article conveys the views of the board of the Nanomedicine and
Nanoscale Delivery Focus Group of the Controlled Release Society regarding the decision …

Nanoparticles for the induction of antigen-specific immunological tolerance

TK Kishimoto, RA Maldonado - Frontiers in immunology, 2018 - frontiersin.org
Antigen-specific immune tolerance has been a long-standing goal for immunotherapy for the
treatment of autoimmune diseases and allergies and for the prevention of allograft rejection …

The use of iron oxide nanoparticles to reprogram macrophage responses and the immunological tumor microenvironment

V Mulens-Arias, JM Rojas, DF Barber - Frontiers in immunology, 2021 - frontiersin.org
The synthesis and functionalization of iron oxide nanoparticles (IONPs) is versatile, which
has enhanced the interest in studying them as theranostic agents over recent years. As …

Nanoparticle-aided characterization of arterial endothelial architecture during atherosclerosis progression and metabolic therapy

TJ Beldman, TS Malinova, E Desclos, AE Grootemaat… - ACS …, 2019 - ACS Publications
Atherosclerosis is associated with a compromised endothelial barrier, facilitating the
accumulation of immune cells and macromolecules in atherosclerotic lesions. In this study …