Diverse immune functions of hemocyanins

CJ Coates, J Nairn - Developmental & Comparative Immunology, 2014 - Elsevier
Substantial evidence gathered recently has revealed the multiple functionalities of
hemocyanin. Contrary to previous claims that this ancient protein is involved solely in …

Immunological properties of oxygen-transport proteins: hemoglobin, hemocyanin and hemerythrin

CJ Coates, H Decker - Cellular and Molecular Life Sciences, 2017 - Springer
It is now well documented that peptides with enhanced or alternative functionality (termed
cryptides) can be liberated from larger, and sometimes inactive, proteins. A primary example …

Marine mollusks: Food with benefits

BM Khan, Y Liu - Comprehensive reviews in food science and …, 2019 - Wiley Online Library
The extremely vast biodiversity represented by marine mollusks alongside their widespread
utility as a source of food and their high nutritional value has aroused great interest from the …

Marine snails and slugs: A great place to look for antiviral drugs

VT Dang, K Benkendorff, T Green, P Speck - Journal of virology, 2015 - Am Soc Microbiol
Molluscs, comprising one of the most successful phyla, lack clear evidence of adaptive
immunity and yet thrive in the oceans, which are rich in viruses. There are thought to be …

Multifunctional roles of hemocyanins

CJ Coates, EM Costa-Paiva - … proteins, lipoproteins and other body fluid …, 2020 - Springer
The copper-containing hemocyanins are proteins responsible for the binding, transportation
and storage of dioxygen within the blood (hemolymph) of many invertebrates. Several …

Dephosphorylation of T517 on Hemocyanin Is Required for Antibacterial Activity in Penaeus vannamei

Q Feng, JJ Aweya, YQ Huang, P Zhang… - The Journal of …, 2023 - journals.aai.org
Posttranslational modifications expand the functions of immune-related proteins, especially
during infections. The respiratory glycoprotein, hemocyanin, has been implicated in many …

Collective locomotion of human cells, wound healing and their control by extracts and isolated compounds from marine invertebrates

C Luparello, M Mauro, V Lazzara, M Vazzana - Molecules, 2020 - mdpi.com
The collective migration of cells is a complex integrated process that represents a common
theme joining morphogenesis, tissue regeneration, and tumor biology. It is known that a …

Molluscan compounds provide drug leads for the treatment and prevention of respiratory disease

K Summer, J Browne, L Liu, K Benkendorff - Marine drugs, 2020 - mdpi.com
Respiratory diseases place an immense burden on global health and there is a compelling
need for the discovery of new compounds for therapeutic development. Here, we identify …

Abalone hemocyanin blocks the entry of herpes simplex virus 1 into cells: a potential new antiviral strategy

N Talaei Zanjani, M Miranda-Saksena… - Antimicrobial agents …, 2016 - Am Soc Microbiol
ABSTRACT A marine-derived compound, abalone hemocyanin, from Haliotis rubra was
shown to have a unique mechanism of antiviral activity against herpes simplex virus 1 (HSV …

Glycosylation of hemocyanin in Litopenaeus vannamei is an antibacterial response feature

Z Zhang, F Wang, C Chen, Z Zheng, JJ Aweya… - Immunology letters, 2017 - Elsevier
Hemocyanin is an important multifunctional non-specific immune molecule. In this study, we
purified lectin binding and non-lectin binding hemocyanin from Litopenaeus vannamei using …