2024 EACTS/EACTAIC Guidelines on patient blood management in adult cardiac surgery in collaboration with EBCP

FPA Casselman, MD Lance, A Ahmed… - European Journal of …, 2024 - academic.oup.com
Cardiac surgery is a distinctive surgical discipline that often necessitates the use of
cardiopulmonary bypass (CPB) and full anticoagulation intraoperatively, along with varying …

Platelet transfusion enhances pro‐aggregatory status shortly after coronary artery bypass grafting (CABG) while modulating platelet pro‐inflammatory state 1‐week …

J Ahmadi, E Hosseini, F Kargar… - Journal of Cellular …, 2024 - Wiley Online Library
During coronary artery bypass grafting (CABG), the surgical procedure, particularly the
manipulation of the major arteries of the heart, induces a significant inflammatory state that …

Fresh frozen plasma transfusion after cardiac surgery

CM Fletcher, JV Hinton, Z Xing, LA Perry… - …, 2025 - journals.sagepub.com
Introduction Fresh frozen plasma (FFP) transfusion in the intensive care unit (ICU) is
commonly used to treat coagulopathy and bleeding in cardiac surgery, despite suggestion …

Platelet transfusion in cardiac surgery: An entropy-balanced, weighted, multicenter analysis

CM Fletcher, JV Hinton, Z Xing, LA Perry… - Anesthesia & …, 2024 - journals.lww.com
BACKGROUND: Platelet transfusion is common in cardiac surgery, but some studies have
suggested an association with harm. Accordingly, we investigated the association of …

Platelet versus fresh frozen plasma transfusion for coagulopathy in cardiac surgery patients

JV Hinton, CM Fletcher, LA Perry, N Greifer, JN Hinton… - Plos one, 2024 - journals.plos.org
Background Platelets (PLTS) and fresh frozen plasma (FFP) are often transfused in cardiac
surgery patients for perioperative bleeding. Their relative effectiveness is unknown. Methods …

Association of perioperative transfusion of fresh frozen plasma and outcomes after cardiac surgery

JV Hinton, Z Xing, C Fletcher, LA Perry… - Acta …, 2024 - Wiley Online Library
Background Fresh frozen plasma (FFP) transfusion is used to manage coagulopathy and
bleeding in cardiac surgery patients despite uncertainty about its safety and effectiveness …

Adjunctive Fresh Frozen Plasma Versus Adjunctive Cryoprecipitate in Cardiac Surgery Patients Receiving Platelets for Perioperative Bleeding

CM Fletcher, JV Hinton, LA Perry, N Greifer… - … of Cardiothoracic and …, 2024 - Elsevier
Objective (s) This study was designed to assess the relative association between adjunctive
fresh frozen plasma (FFP) or adjunctive cryoprecipitate and morbidity and mortality in …

Platelet transfusion trends in cardiac surgery

JV Hinton, CM Fletcher, LA Perry, JN Hinton… - … of Cardiothoracic and …, 2024 - jcvaonline.com
TaggedAPTARAPCARDIAC SURGERY is a major consumer of blood products globally. In
Australia, it is the most common surgical indication for platelet (PLT) transfusion. 1 PLT …

The Significant Role of Point-Of Care Coagulation Studies: Shorter Cardiac Surgery, Better Renal Function and Tranexamic Acid Can Not Alone Reduce Early Platelet …

KL Skidmore, G Borne, A Kallurkar, D Pavlickova… - 2023 - preprints.org
Introduction: In recent years, platelets have been in short supply and high demand.
Approximately one in five cardiac surgery patients require platelets. In our safety-net …

Biomaterials-mediated blood stem cell engineering

A Primbetova - 2023 - open.library.ubc.ca
The field of regenerative medicine and bioengineering presents an exciting opportunity to
harness the potential of hematopoietic stem cells (HSCs) through stem cell niche and …