Parkinson's disease (PD) is a growing burden worldwide, and there is no reliable biomarker
used in clinical routines to date. Cerebrospinal fluid (CSF) is routinely collected in patients …

Mutations on the GBA gene, encoding for the lysosomal enzyme β-glucocerebrosidase
(GCase), have been identified as the most common genetic risk factor involved in the …

Pseudomonas aeruginosa-induced corneal keratitis is a sight-threatening disease. The rise
of antibiotic resistance among P. aeruginosa keratitis isolates makes treatment of this …

Introduction Recent studies have indicated that lysosomal dysfunction contributes to the
development of idiopathic Parkinson's disease (PD). It is uncertain whether dysregulation of …

Objective Alzheimer's disease (AD) is a neurodegenerative disease characterized by
neuropathology and cognitive decline and associated with age. The comprehensive …

Parkinson's disease (PD) is a growing burden worldwide, and despite ongoing efforts to find
reliable biomarkers for early and differential diagnosis, prognosis and disease monitoring …

An accurate and early diagnosis of degenerative parkinsonian syndromes is a major need
for their correct and timely therapeutic management. The current diagnostic criteria are …