Stabilizing biocatalysts

AS Bommarius, MF Paye - Chemical Society Reviews, 2013 - pubs.rsc.org
The area of biocatalysis itself is in rapid development, fueled by both an enhanced
repertoire of protein engineering tools and an increasing list of solved problems …

Ionic liquids as a potential tool for drug delivery systems

N Adawiyah, M Moniruzzaman, S Hawatulaila… - …, 2016 - pubs.rsc.org
The pharmaceutical industries face a series of challenges in the delivery of many newly
developed drug molecules because of their low solubility, bioavailability, stability and …

Effect of ionic liquid on activity, stability, and structure of enzymes: a review

M Naushad, ZA ALOthman, AB Khan, M Ali - International journal of …, 2012 - Elsevier
Ionic liquids have shown their potential as a solvent media for many enzymatic reactions as
well as protein preservation, because of their unusual characteristics. It is also observed that …

Proteins in ionic liquids: current status of experiments and simulations

C Schröder - Ionic liquids II, 2018 - Springer
In the last two decades, while searching for interesting applications of ionic liquids as potent
solvents, their solvation properties and their general impact on biomolecules, and in …

Recent advances in the applications of ionic liquids in protein stability and activity: a review

R Patel, M Kumari, AB Khan - Applied biochemistry and biotechnology, 2014 - Springer
Room temperatures ionic liquids are considered as miraculous solvents for biological
system. Due to their inimitable properties and large variety of applications, they have been …

Contemporary advancement of cholinium-based ionic liquids for protein stability and long-term storage: Past, present, and future outlook

A Sindhu, S Kumar, P Venkatesu - ACS Sustainable Chemistry & …, 2022 - ACS Publications
In the past two decades, ionic liquids (ILs) have been acknowledged as potentially attractive
“green” and “designer” solvents since their broader chemical space and the tunable nature …

Ionic liquids as biocompatible stabilizers of proteins

M Reslan, V Kayser - Biophysical reviews, 2018 - Springer
Ionic liquids (ILs) have recently emerged as versatile solvents and additives in the field of
biotechnology, particularly as stabilizers of proteins and enzymes. Of interest to the …

Biocompatibility of ionic liquids towards protein stability: A comprehensive overview on the current understanding and their implications

A Kumar, M Bisht, P Venkatesu - International journal of biological …, 2017 - Elsevier
Over the past years since the discovery of ionic liquids (ILs), there is an increased demand
to consider ILs as novel biocompatible co-solvents for proteins. Due to their tunable physical …

Enhanced extraction of proteins using cholinium‐based ionic liquids as phase‐forming components of aqueous biphasic systems

MV Quental, M Caban, MM Pereira… - Biotechnology …, 2015 - Wiley Online Library
Aqueous biphasic systems (ABS) composed of ionic liquids (ILs) are promising platforms for
the extraction and purification of proteins. In this work, a series of alternative and …

Rational design to improve protein thermostability: recent advances and prospects

H Yang, L Liu, J Li, J Chen, G Du - ChemBioEng Reviews, 2015 - Wiley Online Library
Research on proteins is in rapid development, but the use of wild‐type proteins under
industrial conditions has limitations, low thermostability in particular. Thermal stability …