1.1. General Considerations Structural intricacies of carbohydrate molecules and their
propensity to form varied linkages, substitutions, and branching patterns have fascinated …

Non-alcoholic fatty liver disease (NAFLD) is a multifaceted metabolic disorder, whose
spectrum covers clinical, histological and pathophysiological developments ranging from …

Non-Alcoholic Fatty Liver Disease (NAFLD) is currently the most common cause of chronic
liver disease worldwide, and its prevalence is increasing globally. NAFLD is a multifaceted …

Glycans are sequences of carbohydrates that are added to proteins or lipids to modulate
their structure and function. Glycans modify proteins required for regulation of immune cells …

The development of non invasive biomarkers of disease has become a major focus of
interest in nonalcoholic fatty liver disease (NAFLD). The large prevalence of the disease and …

Acute phase proteins (APPs) are a group of circulating plasma proteins which undergo
changes quantitatively or qualitatively at the time of inflammation. Many of these APPs are …

The underlying mechanism and pathogenesis of NAFLD remain elusive despite ongoing
researches to make significant advances in the understanding of its natural history …

Background & Aims N‐linked glycosylation of proteins is critical for proper protein folding
and trafficking to the plasma membrane. Drug transporters are one class of proteins that …

Liver fibrosis is currently assessed by liver biopsy, a costly and rather cumbersome
procedure that is unsuitable for frequent patient monitoring, which drives research into …

Nonalcoholic fatty liver disease (NAFLD) affects approximately 25‐30% population
worldwide, which progresses from simple steatosis to nonalcoholic steatohepatitis (NASH) …