Context-specific regulation of extracellular vesicle biogenesis and cargo selection

AC Dixson, TR Dawson, D Di Vizio… - … Reviews Molecular Cell …, 2023 - nature.com
To coordinate, adapt and respond to biological signals, cells convey specific messages to
other cells. An important aspect of cell–cell communication involves secretion of molecules …

The emerging role of Raman spectroscopy as an omics approach for metabolic profiling and biomarker detection toward precision medicine

G Cutshaw, S Uthaman, N Hassan… - Chemical …, 2023 - ACS Publications
Omics technologies have rapidly evolved with the unprecedented potential to shape
precision medicine. Novel omics approaches are imperative toallow rapid and accurate data …

Tracking of extracellular vesicles' biodistribution: new methods and approaches

AM Aimaletdinov, MO Gomzikova - International Journal of Molecular …, 2022 - mdpi.com
Extracellular vesicles (EVs) are nanosized lipid bilayer vesicles that are released by almost
all cell types. They range in diameter from 30 nm to several micrometres and have the ability …

The role of the metabolite cargo of extracellular vesicles in tumor progression

M Harmati, M Bukva, T Böröczky, K Buzás… - Cancer and Metastasis …, 2021 - Springer
Metabolomic reprogramming in tumor and stroma cells is a hallmark of cancer but
understanding its effects on the metabolite composition and function of tumor-derived …

CMOS SPAD line sensor with fine-tunable parallel connected time-to-digital converters for Raman spectroscopy

T Talala, E Parkkinen, I Nissinen - IEEE Journal of Solid-State …, 2022 - ieeexplore.ieee.org
A 256-channel single-photon avalanche diode (SPAD) line sensor was designed for time-
resolved Raman spectroscopy in 110-nm CMOS technology. The line sensor consists of an …

Self-Referenced Au Nanoparticles-Coated Glass Wafers for In Situ SERS Monitoring of Cell Secretion

Z Zhang, C Liu, J Dong, A Zhu, C An, D Wang, X Mi… - ACS …, 2024 - ACS Publications
Surface-enhanced Raman spectroscopy (SERS) is a powerful technique for discrimination
of bimolecules in complex systems. However, its practical applications face challenges such …

A new peptide-mediated COF nanocatalytic amplification SERS quantitative assay for ultratrace Cu2+

Y Shu, S Zhi, S Li, A Liang, Z Jiang - Journal of Industrial and Engineering …, 2022 - Elsevier
Peptides are an important recognition element for small molecules and have been used in
the field of biological analysis. However, it has been rarely reported that a novel method …

[HTML][HTML] Hypoxia as a critical player in extracellular vesicles-mediated intercellular communication between tumor cells and their surrounding microenvironment

H Branco, CPR Xavier, C Riganti… - Biochimica et Biophysica …, 2024 - Elsevier
In the past years, increasing attention has been paid to the role of extracellular vesicles
(EVs) as mediators of intercellular communication in cancer. These small size particles …

Emerging micro-nanotechnologies for extracellular vesicles in immuno-oncology: From target specific isolations to immunomodulation

NE Onukwugha, YT Kang, S Nagrath - Lab on a Chip, 2022 - pubs.rsc.org
Extracellular vesicles (EVs) have been hypothesized to incorporate a variety of crucial roles
ranging from intercellular communication to tumor pathogenesis to cancer immunotherapy …

[HTML][HTML] Revealing the presence of tear extracellular vesicles in Keratoconus

BS Hefley, C Deighan, B Vasini, A Khan… - Experimental eye …, 2022 - Elsevier
Extracellular vesicles (EVs) are lipid-bound vesicles that originate from the endosomal
system or budded off from the plasma membrane. EVs are involved in cell-cell …