Giving voice to the end-user: input on multipurpose prevention technologies from the perspectives of young women in Kenya and South Africa

AM Minnis, E Krogstad, MK Shapley-Quinn… - Sexual and …, 2021 - Taylor & Francis
Unintended pregnancy and unmet need for modern contraception contribute substantially to
reproductive health disparities globally. In sub-Saharan Africa they occur in contexts of …

Barriers and facilitators to uptake and use of oral pre-exposure prophylaxis in pregnant and postpartum women: a qualitative meta-synthesis

Y Liu, L Zhang, H Chen - BMC Public Health, 2024 - Springer
Background Acute HIV infection during pregnancy and in the postpartum period increases
the risk of vertical transmission. The World Health Organization (WHO) has recommended …

Couples' preferences for “2 in 1” multipurpose prevention technologies to prevent both HIV and pregnancy: results of a discrete choice experiment in Uganda and …

AM Minnis, J Etima, P Musara, EN Browne, P Mutero… - AIDS and Behavior, 2022 - Springer
End-user input early in biomedical product development may optimize design to support
high uptake and adherence. We interviewed 400 couples (800 total participants) in Uganda …

Acceptability of the dapivirine vaginal ring for HIV-1 prevention and association with adherence in a phase III trial

AJ Mayo, EN Browne, ET Montgomery, K Torjesen… - AIDS and Behavior, 2021 - Springer
We evaluated the acceptability of the 25 mg dapivirine vaginal ring (DVR) as an HIV
prevention intervention and its influence on DVR adherence in the MTN-020/ASPIRE phase …

Baseline and time‐updated factors in preclinical development of anionic dendrimers as successful anti‐HIV‐1 vaginal microbicides

I Rodríguez‐Izquierdo… - Wiley …, 2022 - Wiley Online Library
Although a wide variety of topical microbicides provide promising in vitro and in vivo efficacy,
most of them failed to prevent sexual transmission of human immunodeficiency virus type 1 …

Baseline preferences for oral pre-exposure prophylaxis (PrEP) or dapivirine intravaginal ring for HIV prevention among adolescent girls and young women in South …

K Ngure, BA Friedland, DW Szydlo, ST Roberts… - Plos one, 2023 - journals.plos.org
Introduction Adolescent girls and young women (AGYW) in sub-Saharan Africa are
disproportionately affected by the HIV epidemic and face an array of challenges using …

Understanding PrEP decision making among pregnant women in Lilongwe, Malawi: A mixed‐methods study

LM Hill, CE Golin, F Saidi, T Phanga… - African Journal of …, 2022 - journals.lww.com
Abstract Introduction: Pre-exposure prophylaxis (PrEP) is a promising tool for HIV prevention
during pregnancy. With increasing rollout in antenatal settings, counselling strategies to help …

Microarray patch for HIV prevention and as a multipurpose prevention technology to prevent HIV and unplanned pregnancy: an assessment of potential acceptability …

SG Gachigua, R Karuga, A Ngunjiri… - … in Reproductive Health, 2023 - frontiersin.org
Background Microarray patches (MAPs), a novel drug delivery system, are being developed
for HIV pre-exposure prophylaxis (PrEP) delivery and as a multipurpose prevention …

Phase 1 pharmacokinetics and safety study of extended duration dapivirine vaginal rings in the United States

AY Liu, C Dominguez Islas… - Journal of the …, 2021 - Wiley Online Library
Introduction Vaginal rings are a promising approach to provide a woman‐centred, long‐
acting HIV prevention strategy. Prior trials of a 25 mg dapivirine (DPV) ring have shown a …

Tu'Washindi na PrEP: working with young women and service providers to design an intervention for PREP uptake and adherence in the context of gender-based …

M Hartmann, S Otticha, K Agot, AM Minnis… - AIDS education and …, 2021 - Guilford Press
HIV pre-exposure prophylaxis (PrEP) reduces HIV acquisition among adolescent girls and
young women (AGYW). Existing evidence suggests that uptake and adherence are low …