Near‐infrared (NIR) activatable fluorescent probes have been considered to be the effective
edge tools for the investigation of cell biology and disease diagnosis because of their …

Parkinson's disease (PD), as the second most common neurodegenerative disease, is
caused by complex pathological processes and currently remains very difficult to treat. PD …

Abnormal expression of proteins, including catalytic and expression dysfunction, is directly
related to the development of various diseases in living organisms. Reactive oxygen species …

Evidence shows that the enzyme human cytochrome P450 1A1 (CYP1A1) is associated with
cancer; indeed, it is shown to play a key role in the occurrence of many cancers. Therefore …

Abstract Drug-metabolizing enzymes (DMEs), a diverse group of enzymes responsible for
the metabolic elimination of drugs and other xenobiotics, have been recognized as the …

Tumors, particularly malignant ones, seriously impact human health. Numerous studies
have demonstrated the exceptional potential of metal-based nanosystems, both as drugs …

The high incidence rates and complicated subtypes of prostate cancer (PCa) call for the
demand of the precise diagnostic and therapeutic strategies. Current clinical imaging …

Abstract Monoamine oxidase A (MAO-A), as a vital drug target for various central nervous
system diseases, locates in mitochondria and is mainly responsible for the oxidative …

Introduction Monoamine oxidase (MAO) inhibitors are currently used as antidepressants
(selective MAO-A inhibitors) or as co-adjuvants for neurodegenerative diseases (selective …

Metabolic reprogramming is one of the main hallmarks of cancer cells. It refers to the
metabolic adaptations of tumor cells in response to nutrient deficiency, microenvironmental …