Objective: The aim was to provide guidelines for evaluation, treatment, and genetic testing
for multiple endocrine neoplasia type 1 (MEN1). Participants: The group, which comprised …

Multiple endocrine neoplasia type 1 (MEN1) is a rare hereditary tumor syndrome inherited in
an autosomal dominant manner and characterized by a predisposition to a multitude of …

Neuroendocrine neoplasms (NENs) are rare neoplasms that occur in various organs and
present with diverse clinical manifestations. Pathological classification is important in the …

Therapeutic approaches for management of metastatic disease include surgical, medical,
radiological and nuclear medicine strategies. More recently, novel molecular targeted drugs …

Neuroendocrine gastroenteropancreatic tumors (GEP-NETs) constitute a heterogeneous
group of tumors with their origin in neuroendocrine cells of the embryological gut. Most …

Multiple endocrine neoplasia (MEN) is characterized by the occurrence of tumors involving
two or more endocrine glands within a single patient. Four major forms of MEN, which are …

Gastrinomas are neuroendocrine neoplasms, usually located in the duodenum or pancreas,
that secrete gastrin and cause a clinical syndrome known as Zollinger-Ellison syndrome …

Well-differentiated neuroendocrine tumors (NETs) of the stomach and pancreas represent 2
major subtypes of gastrointestinal NETs. Historically, there has been little consensus on the …

Pancreatic endocrine tumors (PETs) have long fascinated clinicians and investigators
despite their relative rarity. Their clinical presentation varies depending on whether the …

Pancreatic endocrine tumors (PETs) have long fascinated clini-cians, because some can
release biologically active hormones that cause distinct syndromes and provide important …