Cell-free biology is the activation of biological processes without the use of intact living cells.
It has been used for more than 50 years across the life sciences as a foundational research …

Cell-free gene expression (CFE) emerged as an alternative approach to living cells for
specific applications in protein synthesis and labelling for structural biology and proteomics …

Integrating synthetic biology into wearables could expand opportunities for noninvasive
monitoring of physiological status, disease states and exposure to pathogens or toxins …

Recent years have seen substantial efforts aimed at constructing artificial cells from various
molecular components with the aim of mimicking the processes, behaviours and …

Cell-free protein synthesis (CFPS) is a platform technology that provides new opportunities
for protein expression, metabolic engineering, therapeutic development, education, and …

The construction of artificial cells from inanimate molecular building blocks is one of the
grand challenges of our time. In addition to being used as simplified cell models to decipher …

Advances in biosensor engineering have enabled the design of programmable molecular
systems to detect a range of pathogens, nucleic acids, and chemicals. Here, we engineer …

Recent advances in cell-free synthetic biology have given rise to gene circuit-based sensors
with the potential to provide decentralized and low-cost molecular diagnostics. However, it …

The new generation of cell-free gene expression systems enables the prototyping and
engineering of biological systems in vitro over a remarkable scope of applications and …

The field of synthetic biology has used the engineered assembly of synthetic gene networks
to create a wide range of functions in biological systems. To date, gene-circuit-based …