Two decades ago, theoretical model calculations played a truly minor role in understanding
mechanisms of redox-active metalloenzymes. The methods available to treat transition …

Abstract Acetylene, HC≡ CH, is one of the primary building blocks in synthetic organic and
industrial chemistry. Several highly valuable processes have been developed based on this …

The ketocarotenoid fucoxanthin and its derivatives can absorb blue–green light enriched in
marine environments. Fucoxanthin is widely adopted by phytoplankton species as a main …

Over the past two decades, prominent importance of molybdenum-containing enzymes in
prokaryotes has been put forward by studies originating from different fields. Proteomic or …

We report systematic quantum mechanics‐only (QM‐only) and QM/molecular mechanics
(MM) calculations on an enzyme‐catalyzed reaction to assess the convergence behavior of …

Tungsten is widely distributed in biology, however, the majority of the tungsten-containing
enzymes purified to date, originates from anaerobic archaea and bacteria. Tungsten …

Molybdenum pterin cofactor-containing enzymes exist in all domains of life and their
importance is exemplified by their ubiquity, their roles in metabolic diversity and global …

Tungsten is the heaviest element used in biological systems. It occurs in the active sites of
several bacterial or archaeal enzymes and is ligated to an organic cofactor (metallopterin or …

The direct enantioselective addition of water to unactivated alkenes could simplify the
synthesis of chiral alcohols and solve a long‐standing challenge in catalysis. Here we report …

Molybdenum and tungsten enzymes which contain the pyranopterin cofactor are ubiquitous
in Nature and perform a wide variety of biological functions. They catalyze a diversity of …