Vaccines against candidiasis: Status, challenges and emerging opportunity

SR Sahu, S Bose, M Singh, P Kumari… - Frontiers in Cellular …, 2022 - frontiersin.org
Candidiasis is a mycosis caused by opportunistic Candida species. The occurrence of
fungal infections has considerably increased in the last few years primarily due to an …

Recent progress in vaccines against fungal diseases

A Cassone, A Casadevall - Current opinion in microbiology, 2012 - Elsevier
Diseases caused by fungi are increasingly impacting the health of the human population
and now account for a large fraction of infectious disease complications in individuals with …

The Elusive Anti-Candida Vaccine: Lessons From the Past and Opportunities for the Future

GHW Tso, JA Reales-Calderon, N Pavelka - Frontiers in Immunology, 2018 - frontiersin.org
Candidemia is a bloodstream fungal infection caused by Candida species and is most
commonly observed in hospitalized patients. Even with proper antifungal drug treatment …

Vaccination with Live or Heat-Killed Aspergillus fumigatus ΔsglA Conidia Fully Protects Immunocompromised Mice from Invasive Aspergillosis

CM Fernandes, TG Normile, JHTM Fabri, VS Brauer… - MBio, 2022 - Am Soc Microbiol
Aspergillus fumigatus causes invasive aspergillosis (IA) in immunocompromised patients,
resulting in high mortality rates. Currently, no vaccine formulations to promote immune …

[PDF][PDF] Invasive fungal infections: a comprehensive review

SD Rao - Am J Infect Dis, 2013 - Citeseer
Fungi are a versatile group of microorganisms which can be freely present in the
environment, be a part of the normal flora of human and animals and have the ability to …

Fungal cell wall vaccines: an update

JE Edwards Jr - Journal of medical microbiology, 2012 - microbiologyresearch.org
This discussion is intended to be an overview of current advances in the development of
fungal cell wall vaccines with an emphasis on Candida; it is not a comprehensive historical …

Proteomic analysis of pathogenic fungi reveals highly expressed conserved cell wall proteins

J Champer, JI Ito, KV Clemons, DA Stevens, M Kalkum - Journal of Fungi, 2016 - mdpi.com
We are presenting a quantitative proteomics tally of the most commonly expressed
conserved fungal proteins of the cytosol, the cell wall, and the secretome. It was our goal to …

Advances in fungal peptide vaccines

L BR Da Silva, C P. Taborda, J D. Nosanchuk - Journal of fungi, 2020 - mdpi.com
Vaccination is one of the greatest public health achievements in the past century, protecting
and improving the quality of life of the population worldwide. However, a safe and effective …

Current trends to control fungal pathogens: exploiting our knowledge in the host-pathogen interaction

LC García-Carnero, LA Pérez-García… - Infection and Drug …, 2018 - Taylor & Francis
Human fungal infections remain a major challenge in medicine. Only a limited number of
antifungal drugs are available, which are often related to severe adverse effects. In addition …

Whole glucan particles as a vaccine against murine aspergillosis

KV Clemons, ME Danielson… - Journal of medical …, 2014 - microbiologyresearch.org
Vaccination with heat-killed Saccharomyces cerevisiae (HKY) protects against experimental
infection by pathogenic fungi of five genera. Here we tested whether purified …