A Brownian ratchet for protein translocation including dissociation of ratcheting sites
A Depperschmidt, N Ketterer, P Pfaffelhuber - Journal of mathematical …, 2013 - Springer
We study a model for the translocation of proteins across membranes through a nanopore
using a ratcheting mechanism. When the protein enters the nanopore it diffuses in and out of …
using a ratcheting mechanism. When the protein enters the nanopore it diffuses in and out of …
A top-down approach to mechanistic biological modeling: application to the single-chain antibody folding pathway
S Hildebrandt, D Raden, L Petzold, AS Robinson… - Biophysical …, 2008 - cell.com
A top-down approach to mechanistic modeling of biological systems is presented and
exemplified with the development of a hypothesis-driven mathematical model for single …
exemplified with the development of a hypothesis-driven mathematical model for single …
Realistic extensions of a Brownian ratchet for protein translocation
A Depperschmidt, N Ketterer, P Pfaffelhuber - arXiv preprint arXiv …, 2011 - arxiv.org
We study a model for the translocation of proteins across membranes through a nanopore
using a ratcheting mechanism. When the protein enters the nanopore it diffuses in and out of …
using a ratcheting mechanism. When the protein enters the nanopore it diffuses in and out of …