Myeloperoxidase (MPO) is a member of the superfamily of heme peroxidases that is mainly
expressed in neutrophils and monocytes. MPO-derived reactive species play a key role in …

Oxidative stress and cardiovascular disease: new insights Page 1 Address for correspondence:
Prof. Francesco Violi, I Clinica Medica, Viale del Policlinico 155, Roma, 00161, Italy, tel …

Peripheral artery disease (PAD), which consists of partial or complete obstruction of the
arteries in the lower limbs, is one of the most common manifestations of atherosclerosis …

Inflammation can extend ischemic brain injury and adversely affect outcome in experimental
animal models. A key difficulty in translating animal studies to humans is the lack of a …

Background: Inflammation and oxidative stress are associated with atherosclerosis.
Myeloperoxidase (MPO) is linked to both inflammation and oxidative stress by its location in …

Significance: The incidence of cardiovascular events (CVEs) increases with age,
representing the main cause of death in an elderly population. Aging is associated with …

Myeloperoxidase (MPO), a heme protein released by leukocytes, is one of the most widely
studied during the last decades molecule that plays a crucial role in inflammation and …

Objective: Patients with lower extremity peripheral artery disease (PAD) are at increased risk
of major adverse cardiovascular events. Numerous plasma biomarkers have been …

Myeloperoxidase (MPO) is a prominent mammalian heme peroxidase and a fundamental
component of the innate immune response against microbial pathogens. In recent times …

Significance: Myeloperoxidase (MPO) is a heme peroxidase that is primarily expressed by
neutrophils. It has the capacity to generate several reactive species, essential for its inherent …