Neuronal reward and decision signals: from theories to data

W Schultz - Physiological reviews, 2015 - journals.physiology.org
Rewards are crucial objects that induce learning, approach behavior, choices, and
emotions. Whereas emotions are difficult to investigate in animals, the learning function is …

What the orbitofrontal cortex does not do

TA Stalnaker, NK Cooch, G Schoenbaum - Nature neuroscience, 2015 - nature.com
The number of papers about the orbitofrontal cortex (OFC) has grown from 1 per month in
1987 to a current rate of over 50 per month. This publication stream has implicated the OFC …

[HTML][HTML] Orbitofrontal cortex uses distinct codes for different choice attributes in decisions motivated by curiosity

TC Blanchard, BY Hayden, ES Bromberg-Martin - Neuron, 2015 - cell.com
Decision makers are curious and consequently value advance information about future
events. We made use of this fact to test competing theories of value representation in area …

Reward value comparison via mutual inhibition in ventromedial prefrontal cortex

CE Strait, TC Blanchard, BY Hayden - Neuron, 2014 - cell.com
Recent theories suggest that reward-based choice reflects competition between value
signals in the ventromedial prefrontal cortex (vmPFC). We tested this idea by recording …

Dynamic salience processing in paraventricular thalamus gates associative learning

Y Zhu, G Nachtrab, PC Keyes, WE Allen, L Luo, X Chen - Science, 2018 - science.org
The salience of behaviorally relevant stimuli is dynamic and influenced by internal state and
external environment. Monitoring such changes is critical for effective learning and flexible …

An oxytocin-induced facilitation of neural and emotional responses to social touch correlates inversely with autism traits

D Scheele, KM Kendrick, C Khouri, E Kretzer… - …, 2014 - nature.com
Social communication through touch and mutual grooming can convey highly salient socio-
emotional signals and has been shown to involve the neuropeptide oxytocin (OXT) in …

Disentangling neural representations of value and salience in the human brain

T Kahnt, SQ Park, JD Haynes… - Proceedings of the …, 2014 - National Acad Sciences
A large body of evidence has implicated the posterior parietal and orbitofrontal cortex in the
processing of value. However, value correlates perfectly with salience when appetitive …

The dopamine prediction error: contributions to associative models of reward learning

HM Nasser, DJ Calu, G Schoenbaum… - Frontiers in …, 2017 - frontiersin.org
Phasic activity of midbrain dopamine neurons is currently thought to encapsulate the
prediction-error signal described in model-free reinforcement learning algorithm. This phasic …

Targeted stimulation of human orbitofrontal networks disrupts outcome-guided behavior

JD Howard, R Reynolds, DE Smith, JL Voss… - Current Biology, 2020 - cell.com
Outcome-guided behavior requires knowledge about the current value of expected
outcomes. Such behavior can be isolated in the reinforcer devaluation task, which assesses …

Dopamine error signal to actively cope with lack of expected reward

S Ishino, T Kamada, GA Sarpong, J Kitano… - Science …, 2023 - science.org
To obtain more of a particular uncertain reward, animals must learn to actively overcome the
lack of reward and adjust behavior to obtain it again. The neural mechanisms underlying …