Effect of hesperidin on cardiovascular disease risk factors: the role of intestinal microbiota on hesperidin bioavailability

A Mas-Capdevila, J Teichenne, C Domenech-Coca… - Nutrients, 2020 - mdpi.com
Recently, hesperidin, a flavonone mainly present in citrus fruits, has emerged as a new
potential therapeutic agent able to modulate several cardiovascular diseases (CVDs) risk …

Effects of the treatment with flavonoids on metabolic syndrome components in humans: A systematic review focusing on mechanisms of action

HJCB Gouveia, MV Urquiza-Martínez… - International journal of …, 2022 - mdpi.com
Diets high in bioactive compounds, such as polyphenols, have been used to mitigate
metabolic syndrome (MetS). Polyphenols are a large group of naturally occurring bioactive …

Hesperetin as an anti-SARS-CoV-2 agent can inhibit COVID-19-associated cancer progression by suppressing intracellular signaling pathways

H Zalpoor, M Bakhtiyari, H Shapourian… - …, 2022 - Springer
Hesperetin, an aglycone metabolite of hesperidin with high bioavailability, recently gained
attention due to its anti-COVID-19 and anti-cancer properties. Multiple studies revealed that …

Prevention of metabolic syndrome by phytochemicals and vitamin D

K Santa, Y Kumazawa, I Nagaoka - International Journal of Molecular …, 2023 - mdpi.com
In recent years, attention has focused on the roles of phytochemicals in fruits and vegetables
in maintaining and improving the intestinal environment and preventing metabolic …

The role of nutrition on meta-inflammation: insights and potential targets in communicable and chronic disease management

O Ramos-Lopez, D Martinez-Urbistondo… - Current Obesity …, 2022 - Springer
Abstract Purpose of Review Chronic low-grade inflammation may contribute to the onset and
progression of communicable and chronic diseases. This review examined the effects and …

A narrative review on the role of hesperidin on metabolic parameters, liver enzymes, and inflammatory markers in nonalcoholic fatty liver disease

N Morshedzadeh, A Ramezani Ahmadi… - Food Science & …, 2023 - Wiley Online Library
Insulin resistance, oxidative stress, hyperlipidemia, and inflammation play main roles in the
development of nonalcoholic fatty liver disease (NAFLD). Some studies have reported that …

Hesperetin, a promising treatment option for diabetes and related complications: A literature review

H Yang, Y Wang, S Xu, J Ren, L Tang… - Journal of Agricultural …, 2022 - ACS Publications
The morbidity and mortality of diabetes have increased dramatically in recent decades.
Novel strategies for treating diabetes and its complications with minimal side effects are in …

The effect of dietary interventions on hypertriglyceridemia: from public health to molecular nutrition evidence

KP Luna-Castillo, XC Olivares-Ochoa… - Nutrients, 2022 - mdpi.com
Approximately 25–50% of the population worldwide exhibits serum triglycerides (TG)(≥ 150
mg/dL) which are associated with an increased level of highly atherogenic remnant-like …

The effects of hesperidin supplementation on cardiovascular risk factors in adults: a systematic review and dose–response meta-analysis

AS Khorasanian, ST Fateh, F Gholami, N Rasaei… - Frontiers in …, 2023 - frontiersin.org
Hesperidin is a naturally occurring bioactive compound that may have an impact on
cardiovascular disease risks, but the evidence is not conclusive. To investigate further, this …

Evaluation of the equivalence of different intakes of Fruitflow in affecting platelet aggregation and thrombin generation capacity in a randomized, double-blinded pilot …

RK Das, T Datta, D Biswas, R Duss, N O'Kennedy… - BMC nutrition, 2021 - Springer
Background The water-soluble tomato extract, Fruitflow® is a dietary antiplatelet which can
be used to lower platelet aggregability in primary preventative settings. We carried out a pilot …