Considering how biological sex impacts immune responses and COVID-19 outcomes

EP Scully, J Haverfield, RL Ursin… - Nature Reviews …, 2020 - nature.com
A male bias in mortality has emerged in the COVID-19 pandemic, which is consistent with
the pathogenesis of other viral infections. Biological sex differences may manifest …

Clinical characteristics of coronavirus disease 2019 (COVID-19) in China: a systematic review and meta-analysis

L Fu, B Wang, T Yuan, X Chen, Y Ao, T Fitzpatrick, P Li… - Journal of Infection, 2020 - Elsevier
Objective To better inform efforts to treat and control the current outbreak with a
comprehensive characterization of COVID-19. Methods We searched PubMed, EMBASE …

Higher mortality of COVID-19 in males: sex differences in immune response and cardiovascular comorbidities

LA Bienvenu, J Noonan, X Wang… - Cardiovascular …, 2020 - academic.oup.com
The high mortality rate of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
infection is a critical concern of the coronavirus disease 2019 (COVID-19) pandemic …

Sex differences in severity and mortality from COVID-19: are males more vulnerable?

A Pradhan, PE Olsson - Biology of sex Differences, 2020 - Springer
Abstract Coronavirus disease 2019 (COVID-19) has shown high infection and mortality rates
all over the world, and despite the global efforts, there is so far no specific therapy available …

COVID-19 and individual genetic susceptibility/receptivity: role of ACE1/ACE2 genes, immunity, inflammation and coagulation. Might the double X-chromosome in …

D Gemmati, B Bramanti, ML Serino… - International journal of …, 2020 - mdpi.com
In December 2019, a novel severe acute respiratory syndrome (SARS) from a new
coronavirus (SARS-CoV-2) was recognized in the city of Wuhan, China. Rapidly, it became …

Sex differences in mortality from COVID-19 pandemic: are men vulnerable and women protected?

G Sharma, AS Volgman, ED Michos - Case Reports, 2020 - jacc.org
Collecting sex-disaggregated data is essential to understanding the risk factors of poor
health, early death, and health inequities. Compared to women, men infected with the 2019 …

Sex disparities matter in cancer development and therapy

S Haupt, F Caramia, SL Klein, JB Rubin… - Nature Reviews …, 2021 - nature.com
Curing cancer through precision medicine is the paramount aim of the new wave of
molecular and genomic therapies. Currently, whether patients with non-reproductive …

Autoimmune and autoinflammatory conditions after COVID-19 vaccination. New case reports and updated literature review

Y Rodríguez, M Rojas, S Beltrán, F Polo… - Journal of …, 2022 - Elsevier
Autoimmunity linked to COVID-19 immunization has been recorded throughout the
pandemic. Herein we present six new patients who experienced relapses of previous …

[HTML][HTML] Do COVID-19 RNA-based vaccines put at risk of immune-mediated diseases? In reply to “potential antigenic cross-reactivity between SARS-CoV-2 and …

R Talotta - Clinical Immunology (Orlando, Fla.), 2021 - ncbi.nlm.nih.gov
I read with great interest the article by Vojdani et al.[1], concerning the hypothesis of a
molecular mimicry mechanism between the nucleoprotein/spike protein of Severe Acute …

[HTML][HTML] The prevalence of autoimmune disorders in women: a narrative review

F Angum, T Khan, J Kaler, L Siddiqui, A Hussain - Cureus, 2020 - ncbi.nlm.nih.gov
Autoimmune disorders are characterized as a condition in which the host's immune system
mistakenly attacks itself. These disorders cause the immune system to cause a systemic …