Neurotoxicity in snakebite—the limits of our knowledge
UK Ranawaka, DG Lalloo… - PLoS neglected tropical …, 2013 - journals.plos.org
Snakebite is classified by the WHO as a neglected tropical disease. Envenoming is a
significant public health problem in tropical and subtropical regions. Neurotoxicity is a key …
significant public health problem in tropical and subtropical regions. Neurotoxicity is a key …
Ending the drought: new strategies for improving the flow of affordable, effective antivenoms in Asia and Africa
The development of snake antivenoms more than a century ago should have heralded
effective treatment of the scourge of snakebite envenoming in impoverished, mostly rural …
effective treatment of the scourge of snakebite envenoming in impoverished, mostly rural …
Pathogenic mechanisms underlying adverse reactions induced by intravenous administration of snake antivenoms
Snake antivenoms are formulations of immunoglobulins, or immunoglobulin fragments,
purified from the plasma of animals immunized with snake venoms. Their therapeutic …
purified from the plasma of animals immunized with snake venoms. Their therapeutic …
Snakebite: When the human touch becomes a bad touch
BG Fry - Toxins, 2018 - mdpi.com
Many issues and complications in treating snakebite are a result of poor human social,
economic and clinical intervention and management. As such, there is scope for significant …
economic and clinical intervention and management. As such, there is scope for significant …
New approaches & technologies of venomics to meet the challenge of human envenoming by snakebites in India
The direct estimate of 46,000 snakebite deaths in India in 2005 (1 for every 2 HIV/AIDS
deaths), based on verbal autopsies, renders unrealistic the total of only 47,000 snakebite …
deaths), based on verbal autopsies, renders unrealistic the total of only 47,000 snakebite …
Recombinant snakebite antivenoms: A cost-competitive solution to a neglected tropical disease?
Snakebite envenoming is a major public health burden in tropical parts of the developing
world. In sub-Saharan Africa, neglect has led to a scarcity of antivenoms threatening the …
world. In sub-Saharan Africa, neglect has led to a scarcity of antivenoms threatening the …
Coagulotoxicity of Bothrops (Lancehead Pit-Vipers) Venoms from Brazil: Differential Biochemistry and Antivenom Efficacy Resulting from Prey-Driven Venom …
Lancehead pit-vipers (Bothrops genus) are an extremely diverse and medically important
group responsible for the greatest number of snakebite envenomations and deaths in South …
group responsible for the greatest number of snakebite envenomations and deaths in South …
Assessing SABU (Serum Anti Bisa Ular), the sole Indonesian antivenom: A proteomic analysis and neutralization efficacy study
Abstract Serum Anti Ular Bisa (SABU) is the only snake antivenom produced locally in
Indonesia; however, its effectiveness has not been rigorously evaluated. This study aimed to …
Indonesia; however, its effectiveness has not been rigorously evaluated. This study aimed to …
Improving antivenom availability and accessibility: science, technology, and beyond
JM Gutiérrez - Toxicon, 2012 - Elsevier
Snakebite envenomings constitute a serious and neglected public health problem. Despite
the fact that effective treatment exists, ie administration of animal-derived antivenoms, the …
the fact that effective treatment exists, ie administration of animal-derived antivenoms, the …
Engineering and design considerations for next-generation snakebite antivenoms
Snakebite envenoming is a devastating Neglected Tropical Disease, the treatment of which
has seen relatively little innovation since the invention of antivenom serotherapy in 1894 …
has seen relatively little innovation since the invention of antivenom serotherapy in 1894 …