Effects of stem cell–derived exosome therapy on erectile dysfunction: a systematic review and meta-analysis of preclinical studies

Y Zhu, T Jiang, C Yao, J Zhang, C Sun, S Chen… - Sexual …, 2023 - academic.oup.com
Introduction Erectile dysfunction (ED) is a common disease among elderly men, and novel
therapy methods are needed for drug-refractory ED. As an extracellular vesicle, stem cell …

Administration of adipose derived mesenchymal stem cells and platelet lysate in erectile dysfunction: a single center pilot study

V Protogerou, E Michalopoulos, P Mallis, I Gontika… - Bioengineering, 2019 - mdpi.com
Erectile dysfunction (ED) affects more than 30 million men; endothelial dysfunction plays a
significant role in EDs pathogenesis. The aim of this study was to administer mesenchymal …

Recycling apparent waste into biologicals: the case of umbilical cord blood in Italy and Spain

P Rebulla, S Querol, S Pupella, D Prati… - Frontiers in Cell and …, 2022 - frontiersin.org
Most public cord blood banking programs are currently facing financial difficulties due to a
progressive decline in the number of cord blood transplants performed worldwide and to a …

The combined use of stem cells and platelet lysate plasma for the treatment of erectile dysfunction: A pilot study–6 months results

V Protogerou, SE Beshari, E Michalopoulos, P Mallis… - Medicines, 2020 - mdpi.com
Background: The current treatment of Erectile Dysfunction (ED) is mainly based on the use
of drugs that provide erections shortly after use but they do not really treat the problem. Stem …

Cord blood platelet rich plasma (PRP) as a potential alternative to autologous PRP for allogenic preparation and regenerative applications

R Mani, P Roopmani, J Rajendran, S Maharana… - International Journal of …, 2024 - Elsevier
As an abundant supplier of growth factors, chemokines and other bioactive molecules,
platelet rich plasma (PRP) become a leading therapy for tissue regeneration. The PRP …

Investigating the production of platelet lysate obtained from low volume Cord Blood Units: Focus on growth factor content and regenerative potential

P Mallis, E Michalopoulos, K Balampanis… - … and Apheresis Science, 2022 - Elsevier
Background The regenerative potential of platelet lysate (PL) and platelet gel (PG) is
mediated by the release of platelets (PLTs) growth factors. The aim of this study was the …

Short term results of fibrin gel obtained from cord blood units: a preliminary in vitro study

P Mallis, I Gontika, Z Dimou, E Panagouli, J Zoidakis… - Bioengineering, 2019 - mdpi.com
Background: Recent findings have shown that the fibrin gel derived from cord blood units
(CBUs) play a significant role in wound healing and tissue regeneration. The aim of this …

[HTML][HTML] Efficient differentiation of vascular smooth muscle cells from Wharton's Jelly mesenchymal stromal cells using human platelet lysate: A potential cell source for …

P Mallis, A Papapanagiotou… - World Journal of Stem …, 2020 - ncbi.nlm.nih.gov
BACKGROUND The development of fully functional small diameter vascular grafts requires
both a properly defined vessel conduit and tissue-specific cellular populations …

Cord blood serum harvesting by hydroxyethyl starch: a fetal bovine serum alternative in expansion of umbilical cord-derived mesenchymal stem cells

M Samareh Salavati Pour, R Vahidi, M Lashkari… - Cytotechnology, 2020 - Springer
As a widely used cell culture supplement, fetal bovine serum (FBS) harbor high content of
growth, proliferation, and adhesion factors. However, high cost, bio-safety, possible …

Selection Criteria of Cord Blood Units for Platelet Gel Production: Proposed Directions from Hellenic Cord Blood Bank. Comment on Mallis et al. Short Term Results of …

P Mallis, E Michalopoulos, E Panagouli, Z Dimou… - Bioengineering, 2021 - mdpi.com
This article provides additional knowledge for cord blood platelet gel (CBPG) production.
Recently, it has been shown that CBPG exerts beneficial properties in wound healing …