Elucidating methods for isolation and quantification of exosomes: a review

TK Kurian, S Banik, D Gopal, S Chakrabarti… - Molecular …, 2021 - Springer
Exosomes are the smallest extracellular vesicles present in most of the biological fluids.
They are found to play an important role in cell signaling, immune response, tumor …

Diagnostic and therapeutic potential of exosomes in Alzheimer's disease

T Soares Martins, D Trindade, M Vaz… - Journal of …, 2021 - Wiley Online Library
Exosomes are small extracellular vesicles released by almost all cell types in physiological
and pathological conditions. The exosomal potential to unravel disease mechanisms, or to …

Glycosylation of cancer extracellular vesicles: capture strategies, functional roles and potential clinical applications

ÁM Martins, CC Ramos, D Freitas, CA Reis - Cells, 2021 - mdpi.com
Glycans are major constituents of extracellular vesicles (EVs). Alterations in the
glycosylation pathway are a common feature of cancer cells, which gives rise to de novo or …

Role of exosomes and exosomal microRNAs in cancer

N Dilsiz - Future science OA, 2020 - Taylor & Francis
A growing body of evidence indicates that exosomes play a critical role in the cell–cell
communication process. Exosomes are biological nanoparticles with an average diameter of …

Aptamer‐functionalized quantum dots as theranostic nanotools against cancer and bacterial infections: a comprehensive overview of recent trends

F Davodabadi, S Mirinejad… - Biotechnology …, 2023 - Wiley Online Library
Aptamers (Apts) are synthetic nucleic acid ligands that can be engineered to target various
molecules, including amino acids, proteins, and pharmaceuticals. Through a series of …

MicroRNAs in extracellular vesicles: sorting mechanisms, diagnostic value, isolation, and detection technology

D Xu, K Di, B Fan, J Wu, X Gu, Y Sun… - … in Bioengineering and …, 2022 - frontiersin.org
MicroRNAs (miRNAs) are a class of short, single-stranded, noncoding RNAs, with a length
of about 18–22 nucleotides. Extracellular vesicles (EVs) are derived from cells and play a …

Extracellular vesicles as biomarkers in cancer immunotherapy

M Mathew, M Zade, N Mezghani, R Patel, Y Wang… - Cancers, 2020 - mdpi.com
Simple Summary Extracellular vesicles (EVs) are small particles found throughout the body.
EVs are released by living cells and contain cargo representing the cell of origin. In recent …

Advanced nanomaterials as sample technique for bio-analysis

N Sun, H Yu, H Wu, X Shen, C Deng - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
The biological compositions including cells, proteins/peptides, nucleic acids, extracellular
vesicles (EVs) and metabolites are no doubt closely related to almost all physiological and …

Fluorescence analysis of circulating exosomes for breast cancer diagnosis using a sensor array and deep learning

Y Jin, N Du, Y Huang, W Shen, Y Tan, YZ Chen… - ACS …, 2022 - ACS Publications
Emerging liquid biopsy methods for investigating biomarkers in bodily fluids such as blood,
saliva, or urine can be used to perform noninvasive cancer detection. However, the …

Advances in analytical technologies for extracellular vesicles

H Yan, Y Li, S Cheng, Y Zeng - Analytical Chemistry, 2021 - ACS Publications
Sensitive early detection, along with effective treatments and solid postoperative monitoring
remain the grand challenges in fighting against human diseases, especially cancer.(1) In …