The placental barrier: the gate and the fate in drug distribution

N Tetro, S Moushaev, M Rubinchik-Stern… - Pharmaceutical …, 2018 - Springer
Optimal development of the embryo and the fetus depends on placental passage of gases,
nutrients, hormones, and waste products. These molecules are transferred across the …

Epigenetics and developmental programming of welfare and production traits in farm animals

KD Sinclair, KMD Rutherford, JM Wallace… - Reproduction …, 2016 - CSIRO Publishing
The concept that postnatal health and development can be influenced by events that occur
in utero originated from epidemiological studies in humans supported by numerous …

Occurrence, placental transfer, and health risks of emerging endocrine-disrupting chemicals in pregnant women

A Li, T Zhuang, M Song, H Cao, Y Gao, S Zheng… - Journal of Hazardous …, 2023 - Elsevier
Previous studies demonstrated that many environmental chemicals can cross the human
placental barrier. However, the risk regarding gestational exposure of emerging endocrine …

Bisphenol A metabolites and bisphenol S in paired maternal and cord serum

J Liu, J Li, Y Wu, Y Zhao, F Luo, S Li… - … science & technology, 2017 - ACS Publications
Human studies show associations between maternal bisphenol A (BPA) exposure and
developmental effects in children, yet biomonitoring of BPA metabolites in maternal and fetal …

Toxicokinetics of bisphenol A, bisphenol S, and bisphenol F in a pregnancy sheep model

J Gingrich, Y Pu, R Ehrhardt, R Karthikraj, K Kannan… - Chemosphere, 2019 - Elsevier
Abstract Bisphenol A (BPA), S (BPS), and F (BPF) are among the most abundant bisphenols
detected in humans, yet pregnancy toxicokinetics for BPS or BPF remain unknown. Because …

Occurrence and maternal transfer of multiple bisphenols, including an emerging derivative with unexpectedly high concentrations, in the human maternal–fetal …

Y Pan, M Deng, J Li, B Du, S Lan… - … science & technology, 2020 - ACS Publications
In this study, a set of 15 bisphenols (BPs) and one emerging derivative (4-hydroxyphenyl 4-
isoprooxyphenylsulfone, BPSIP) were analyzed in 60 pairs of maternal plasma, cord …

Bisphenol A and other phenols in human placenta from children with cryptorchidism or hypospadias

MF Fernández, JP Arrebola, I Jiménez-Díaz… - Reproductive …, 2016 - Elsevier
Embryo-foetal exposure to low doses of endocrine disrupting chemicals (EDCs) has been
related to reproductive tract diseases in experimental animals but not convincingly in human …

Prenatal maternal and childhood bisphenol a exposure and brain structure and behavior of young children

MN Grohs, JE Reynolds, J Liu, JW Martin, T Pollock… - Environmental …, 2019 - Springer
Abstract Background Bisphenol A (BPA) is commonly used in the manufacture of plastics
and epoxy resins. In North America, over 90% of the population has detectable levels of …

Modulatory effects of bisphenol A on the hepatic immune response

YA Gebru, MG Pang - Environmental Pollution, 2023 - Elsevier
The liver is a primary line of defense for protection from external substances next to the
intestinal barrier. As a result, the hepatic immune system plays a central role in liver …

Gestational bisphenol S impairs placental endocrine function and the fusogenic trophoblast signaling pathway

J Gingrich, Y Pu, J Roberts, R Karthikraj, K Kannan… - Archives of …, 2018 - Springer
Exposure to bisphenolic chemicals during pregnancy occurs in> 90% of pregnancies.
Bisphenolic compounds can cross the placental barrier reaching fetal circulation. However …