Omissions, ambiguities, and underuse of causal assessment tools: A systematic review of case reports on patients who use kratom

JD Feldman, D Schriefer, KE Smith, ST Weiss… - Current Addiction …, 2023 - Springer
Purpose of review In this systematic review, we examined case reports of patients who use
kratom and evaluated their rigor based on reporting of clinically relevant information. Recent …

[HTML][HTML] Herbal and dietary supplement induced liver injury: Highlights from the recent literature

SM Woo, WD Davis, S Aggarwal… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Herbal-induced liver injury (HILI) is an important and increasingly concerning cause of liver
toxicity, and this study presents recent updates to the literature. An extensive literature …

Clinical Pharmacology of the Dietary Supplement Kratom (Mitragyna speciosa)

C Hartley, M Bulloch, SR Penzak - The Journal of Clinical …, 2022 - Wiley Online Library
Kratom (Mitragyna speciosa) consists of over 40 alkaloids, with 2 of them, mitragynine and 7‐
OH‐mitragynine (7‐OH‐MG) being the main psychoactive compounds. Mitragynine and 7 …

Case report: treatment of kratom use disorder with a classical tricyclic antidepressant

AE Vento, S De Persis, S De Filippis, F Schifano… - Frontiers in …, 2021 - frontiersin.org
Kratom or Mitragyna speciosa (Korth.) is an evergreen tree of the coffee family native to
South-East Asia and Australasia. It is used by locals recreationally to induce stimulant and …

Two single-drug fatal intoxications by mitragynine

GS Behonick, C Vu, L Czarnecki… - Journal of Analytical …, 2022 - academic.oup.com
Mitragyna speciosa, a species of plant that is native to Thailand, Malaysia and Southeast
Asia, contains two major psychoactive alkaloids: mitragynine and 7-hydroxymitragynine …

Discovery, evaluation, prevention, and control of liver injury risk by Polygoni Multiflori Radix

C Tu, Y Gao, Z Bai, X Xiao, J Wang - Acupuncture and Herbal …, 2024 - journals.lww.com
In recent years, adverse reactions and events associated with traditional Chinese medicines
(TCM) and herbal medicines (HM) have frequently occurred. In particular, with regard to the …

Drug-induced cholestasis: causative agents and challenges in diagnosis and management

JM Pinazo-Bandera, JP Toro-Ortiz… - Exploration of …, 2023 - explorationpub.com
Drug-induced liver injury (DILI) is an adverse reaction to drugs and other xenobiotics that
can have serious consequences and jeopardise progress in pharmacological therapy. While …

[HTML][HTML] Kratom (Mitragyna speciosa)-induced hepatitis

DR Allison, M Mubarak, N Sharma… - ACG Case Reports …, 2022 - journals.lww.com
Kratom is a plant with opioid-like properties known to produce stimulant and analgesic
effects. Although there are numerous studies on the psychoactive components of kratom …

[PDF][PDF] Does Chinese Herbal Medicine Really have Hepatotoxicity?---An In-Depth Analysis Based on a Large Number of Literatures May Reveal Some of the Truth

L He, Y Lu, R Li, J Sun, S Xiong - megajournalofoncology.com
Chinese herbal medicine (CHM), a special drug applied under the guidance of the unique
theory of Chinese medicine, in the past few decades, with its gradual application in the …