Estrogen is a fundamental regulator of the metabolic system of the female brain and body.
Within the brain, estrogen regulates glucose transport, aerobic glycolysis, and mitochondrial …

Males and females sometimes significantly differ in their propensity to develop neurological
disorders. Females suffer more from mood disorders such as depression and anxiety …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that accounts for
more than half of all dementia cases in the elderly. Interestingly, the clinical manifestations of …

Estrogen is an important hormone signal that regulates multiple tissues and functions in the
body. This review focuses on the neurotrophic and neuroprotective actions of estrogen in the …

This review highlights recent evidence from clinical and basic science studies supporting a
role for estrogen in neuroprotection. Accumulated clinical evidence suggests that estrogen …

There is ample empirical evidence to support the notion that the biological impacts of
estrogen extend beyond the gonads to other bodily systems, including the brain and …

ContextSeveral reports from small clinical trials have suggested that estrogen replacement
therapy may be useful for the treatment of Alzheimer disease (AD) in women. ObjectiveTo …

Research in basic neuroscience has provided biological plausibility for the hypothesis that
estrogen replacement therapy (ERT) would protect against cognitive aging in healthy …

In the non‐amyloidogenic pathway, the Alzheimer's amyloid precursor protein (APP) is
cleaved within the amyloid‐β domain by α‐secretase precluding deposition of intact amyloid …

Objective: To determine the relationship between exogenous testosterone administration
and cognitive abilities in a population of healthy older men. Background: Serum levels of …