The elevated plus maze test is used to measure anxiety-like behavior in rodents. It can be
used to gain insight into conditions such as posttraumatic stress disorder (PTSD) and other …

These results support that ketogenic diet may present a novel therapeutic approach through
restoring brain energy metabolism in schizophrenia. Randomized controlled clinical trials …

Feeding is a fundamental process for basic survival and is influenced by genetics and
environmental stressors. Recent advances in our understanding of behavioral genetics have …

Bipolar disorder is a diagnostically heterogeneous disorder, although mania emerges as a
distinct phenotype characterized by elevated mood and increased activity or energy. While …

Schizophrenia (SZ) is a devastating complex genetic mental condition that is heterogeneous
in terms of clinical etiologies, symptoms, and outcomes. Despite decades of postmortem …

Cortical GABAergic dysfunctions have been documented by clinical studies in major
depression. We used here an animal model for depression and investigated whether long …

The use of model organisms as tools for the investigation of human genetic variation has
significantly and rapidly advanced our understanding of the aetiologies underlying …

In order to decipher the disease etiology, progression and treatment of multifactorial human
brain diseases we utilize a host of different experimental models. Recently, patient-derived …

Current schizophrenia (SCZ) treatments fail to treat the broad range of manifestations
associated with this devastating disorder. Thus, new translational models that reproduce the …

There is substantial interest in the N-methyl-d-aspartate (NMDA) receptor antagonist
ketamine in psychiatric research because it exerts acute psychotomimetic and rapid …