MRI-guided radiation therapy: an emerging paradigm in adaptive radiation oncology

R Otazo, P Lambin, JP Pignol, ME Ladd… - Radiology, 2021 - pubs.rsna.org
Radiation therapy (RT) continues to be one of the mainstays of cancer treatment.
Considerable efforts have been recently devoted to integrating MRI into clinical RT planning …

Motion management strategies and technical issues associated with stereotactic body radiotherapy of thoracic and upper abdominal tumors: a review from NRG …

ED Brandner, IJ Chetty, TG Giaddui, Y Xiao… - Medical …, 2017 - Wiley Online Library
The efficacy of stereotactic body radiotherapy (SBRT) has been well demonstrated.
However, it presents unique challenges for accurate planning and delivery especially in the …

AAPM Task Group 264: The safe clinical implementation of MLC tracking in radiotherapy

PJ Keall, A Sawant, RI Berbeco, JT Booth… - Medical …, 2021 - Wiley Online Library
The era of real‐time radiotherapy is upon us. Robotic and gimbaled linac tracking are
clinically established technologies with the clinical realization of couch tracking in …

The first clinical implementation of electromagnetic transponder‐guided MLC tracking

PJ Keall, E Colvill, R O'Brien, JA Ng… - Medical …, 2014 - Wiley Online Library
Purpose: We report on the clinical process, quality assurance, and geometric and dosimetric
results of the first clinical implementation of electromagnetic transponder‐guided MLC …

Failure mode and effect analysis‐based quality assurance for dynamic MLC tracking systems

A Sawant, S Dieterich, M Svatos, P Keall - Medical physics, 2010 - Wiley Online Library
Purpose: To develop and implement a failure mode and effect analysis (FMEA)‐based
commissioning and quality assurance framework for dynamic multileaf collimator (DMLC) …

The first patient treatment of electromagnetic-guided real time adaptive radiotherapy using MLC tracking for lung SABR

JT Booth, V Caillet, N Hardcastle, R O'Brien… - Radiotherapy and …, 2016 - Elsevier
Background and purpose Real time adaptive radiotherapy that enables smaller irradiated
volumes may reduce pulmonary toxicity. We report on the first patient treatment of …

Multileaf collimator tracking improves dose delivery for prostate cancer radiation therapy: results of the first clinical trial

E Colvill, JT Booth, RT O'Brien, TN Eade… - International Journal of …, 2015 - Elsevier
Purpose To test the hypothesis that multileaf collimator (MLC) tracking improves the
consistency between the planned and delivered dose compared with the dose without MLC …

Magnitude, impact, and management of respiration-induced target motion in radiotherapy treatment: a comprehensive review

SA Yoganathan, KJM Das, A Agarwal… - Journal of medical …, 2017 - journals.lww.com
Tumors in thoracic and upper abdomen regions such as lungs, liver, pancreas, esophagus,
and breast move due to respiration. Respiration-induced motion introduces uncertainties in …

comprehensive performance tests of the first clinical real‐time motion tracking and compensation system using MLC and jaws

GP Chen, A Tai, TD Keiper, S Lim, XA Li - Medical physics, 2020 - Wiley Online Library
Purpose To evaluate the performance of the first clinical real‐time motion tracking and
compensation system using multileaf collimator (MLC) and jaws during helical tomotherapy …

DMLC tracking and gating can improve dose coverage for prostate VMAT

E Colvill, PR Poulsen, JT Booth, RT O'Brien… - Medical …, 2014 - Wiley Online Library
Purpose: To assess and compare the dosimetric impact of dynamic multileaf collimator
(DMLC) tracking and gating as motion correction strategies to account for intrafraction …