Blood flow in the microcirculation

TW Secomb - Annual Review of Fluid Mechanics, 2017 - annualreviews.org
The microcirculation is an extensive network of microvessels that distributes blood flow
throughout living tissues. Reynolds numbers are much less than 1, and the equations of …

[HTML][HTML] Hemodynamics

TW Secomb - Comprehensive physiology, 2016 - ncbi.nlm.nih.gov
A review is presented of the physical principles governing the distribution of blood flow and
blood pressure in the vascular system. The main factors involved are the pulsatile driving …

Bacterial transport suppressed by fluid shear

R Rusconi, JS Guasto, R Stocker - Nature physics, 2014 - nature.com
Bacteria often live in dynamic fluid environments,, and flow can affect fundamental microbial
processes such as nutrient uptake, and infection. However, little is known about the …

Microvasculature on a chip: study of the endothelial surface layer and the flow structure of red blood cells

D Tsvirkun, A Grichine, A Duperray, C Misbah… - Scientific reports, 2017 - nature.com
Abstract Microvasculatures-on-a-chip, ie in vitro models that mimic important features of
microvessel networks, have gained increasing interest in recent years. Such devices have …

Microvascular blood flow resistance: role of red blood cell migration and dispersion

D Katanov, G Gompper, DA Fedosov - Microvascular research, 2015 - Elsevier
Microvascular blood flow resistance has a strong impact on cardiovascular function and
tissue perfusion. The flow resistance in microcirculation is governed by flow behavior of …

Microfluidics to mimic blood flow in health and disease

B Sebastian, PS Dittrich - Annual review of fluid mechanics, 2018 - annualreviews.org
Throughout history, capillary systems have aided the establishment of the fundamental laws
of blood flow and its non-Newtonian properties. The advent of microfluidics technology in the …

Fluid vesicles in flow

D Abreu, M Levant, V Steinberg, U Seifert - Advances in colloid and …, 2014 - Elsevier
We review the dynamical behavior of giant fluid vesicles in various types of external
hydrodynamic flow. The interplay between stresses arising from membrane elasticity …

Inversion of hematocrit partition at microfluidic bifurcations

Z Shen, G Coupier, B Kaoui, B Polack, J Harting… - Microvascular …, 2016 - Elsevier
Partitioning of red blood cells (RBCs) at the level of bifurcations in the microcirculatory
system affects many physiological functions yet it remains poorly understood. We address …

Understanding particle margination in blood flow–a step toward optimized drug delivery systems

K Müller, DA Fedosov, G Gompper - Medical engineering & physics, 2016 - Elsevier
Targeted delivery of drugs and imaging agents is very promising to develop new strategies
for the treatment of various diseases such as cancer. For an efficient targeted adhesion, the …

Theory to predict particle migration and margination in the pressure-driven channel flow of blood

QM Qi, ESG Shaqfeh - Physical review fluids, 2017 - APS
The inhomogeneous concentration distribution of erythrocytes and platelets in microchannel
flows particularly in directions normal to the mean flow plays a significant role in hemostasis …