Modifiable contributing factors to COVID-19: A comprehensive review

RN Kostoff, MB Briggs, D Kanduc, S Dewanjee… - Food and Chemical …, 2023 - Elsevier
The devastating complications of coronavirus disease 2019 (COVID-19) result from an
individual's dysfunctional immune response following the initial severe acute respiratory …

Comparative study of the Neurotoxic Effects of Pregabalin versus Tramadol in Rats

AE Elsukary, AMNZ Helaly, AA El Bakary… - Neurotoxicity …, 2022 - Springer
In Egypt, both pregabalin and tramadol misuse increased in the last decade. Although many
studies have confirmed the neurotoxic effects of tramadol, those of pregabalin are …

[PDF][PDF] Histological liver, kidney, and brain changes induced by pregabalin drug in albino rats

BA Salah, MY Al-Fathi, MK Shindala - Iraqi J Vet Sci, 2024 - iasj.net
Pregabalin is a commonly used medication for the treatment of pain associated with
neuropathic conditions, but there has been little research on its harmful consequences. This …

Nano-pregabalin effectively mitigates Glut, CGRP and NE neurotransmitters abnormalities in the brain of gamma irradiated rats with reserpine-induced fibromyalgia …

EM Samy, RR Radwan, FM Mosallam, HA Mohamed - Neuropharmacology, 2024 - Elsevier
Aims Fibromyalgia (FM) is an idiopathic syndrome with painful burdensome symptoms.
Radiotherapy is one of the main therapeutic modalities for treating various malignancies and …

The effects of prenatal exposure to pregabalin on the development of ventral midbrain dopaminergic neurons

WF Alsanie, M Alhomrani, A Gaber, H Habeeballah… - Cells, 2022 - mdpi.com
Pregabalin is widely used as a treatment for multiple neurological disorders; however, it has
been reported to have the potential for misuse. Due to a lack of safety studies in pregnancy …

Pregabalin mediates retinal ganglion cell survival from retinal Ischemia/Reperfusion Injury Via the Akt/GSK3β/β-Catenin signaling pathway

J Xu, Y Guo, Q Liu, H Yang, M Ma, J Yu… - … & Visual Science, 2022 - iovs.arvojournals.org
Purpose: Progressive retinal ganglion cell (RGC) loss induced by retinal
ischemia/reperfusion (RIR) injury leads to irreversible visual impairment. Pregabalin (PGB) …

Can the long term using of pregabalin in fibromyalgia affect the choroid and retinal nerve fiber layer?

GY Biçer, KR Zor, KE Biçer, E Küçük, EB Küçük - Eye, 2022 - nature.com
Background In this study, the effects of long-term pregabalin use on the choroid and retinal
nerve fiber layer were investigated in the fibromyalgia disease. Methods The patient group …

Investigating the effect of pregabalin on neuronal development using ultrashort self-assembling peptides: Assessing 3D neuronal cultures with high throughput robotic …

WF Alsanie, S Abdelrahman, M Alhomrani… - 2024 - repository.kaust.edu.sa
Pregabalin is a widely prescribed drug for various neurological disorders, yet its effects on
embryonic cortical neuron development when given to pregnant women remain …

[PDF][PDF] Comparative Study of the Hepatotoxic and Nephrotoxic Effects of Gabapentin versus Clonazepam in Rats

MA Khattab, FAWA Maksoud, ME Eldein, W Awad… - 2024 - multiarticlesjournal.com
Background: Gabapentin is an anticonvulsant adjunct and a neuropathic pain analgesic that
has become widely abused in Egypt in the last decade after scheduling its analogue …

CLONAZEPAM INDUCED SUB CHRONIC HEPATORENAL TOXICITY IN RATS AND THE PROTECTIVE ROLE OF ALPHA-TOCOPHEROL

MA Khattab, FAW Abdel Maksoud… - The Egyptian Journal …, 2023 - journals.ekb.eg
Background: Clonazepam (CZP) is an antiepileptic drug approved in 1976 by Food and
Drug Administration (FDA) for treatment of various types of seizures, Clonazepam has a high …