Multiple factors combined are currently recognized as contributors to cognitive decline. The
main independent risk factor for cognitive impairment and dementia is advanced age …

Coffee is one of the most widely consumed beverages worldwide. It is usually identified as a
stimulant because of a high content of caffeine. However, caffeine is not the only coffee …

To evaluate the associations between coffee and caffeine consumption and various health
outcomes, we performed an umbrella review of the evidence from meta-analyses of …

The adenosine modulation system mostly operates through inhibitory A1 (A1R) and
facilitatory A2A receptors (A2AR) in the brain. The activity‐dependent release of adenosine …

A systematic review was conducted to identify risk factors associated with the onset and
progression of Alzheimer's disease (AD). Moderate and high quality systematic reviews …

Coffee is popular worldwide and consumption is increasing, particularly in non-traditional
markets. There is evidence that coffee consumption may have beneficial health effects …

Coffee, after water, is the most widely consumed beverage in the United States, and is the
principal source of caffeine intake among adults. The biological effects of coffee may be …

Cocoa powder and chocolate contain numerous substances among which there is a quite
large percentage of antioxidant molecules, mainly flavonoids, most abundantly found in the …

Over the last decade, Food Regulation Authorities have concluded that coffee/caffeine
consumption is not harmful if consumed at levels of 200 mg in one sitting (around 2½ cups of …

The aim of this study was to examine the association of coffee, caffeinated coffee,
decaffeinated coffee and caffeine intake from coffee with cognitive performance in older …