The treatment of cancer with proton radiation therapy was first suggested in 1946 followed
by the first treatments in the 1950s. As of 2020, almost 200 000 patients have been treated …

Background and purpose The use of cone beam computed tomography (CBCT) for
performing dose calculations in radiation therapy has been widely investigated as it could …

Purpose Pencil beam scanned proton therapy (PBS-PT) treatment quality might be
compromised by interplay and motion effects. Via fraction-wise reconstruction of 4D dose …

Background Time‐resolved 4D cone beam–computed tomography (4D‐CBCT) allows a
daily assessment of patient anatomy and respiratory motion. However, 4D‐CBCTs suffer …

Purpose Compared to volumetric modulated arc therapy (VMAT), clinical benefits are
anticipated when treating thoracic tumours with intensity-modulated proton therapy (IMPT) …

Background Clinical evidence has demonstrated that proton therapy can achieve
comparable tumor control probabilities compared to conventional photon therapy but with …

Real-time motion monitoring of lung tumors with low-field magnetic resonance imaging-
guided linear accelerators (MR-Linacs) is currently limited to sagittal 2D cine magnetic …

Background and purpose: In radiotherapy, dose calculations based on 4D cone beam CTs
(4DCBCTs) require image intensity corrections. This retrospective study compared the dose …

Objective: FLASH radiotherapy leverages ultra-high dose-rate radiation to enhance the
sparing of organs at risk without compromising tumor control probability. This may allow …

Proton therapy treatment for lungs remains challenging as images enabling the detection of
inter-and intra-fractional motion, which could be used for proton dose adaptation, are not …