Diabetic foot is a severe public health issue, yet rare studies investigated its global
epidemiology. Here we performed a systematic review and meta-analysis through searching …

Neutrophils promptly accumulate in large numbers at sites of tissue injury. Injuries to the skin
or mucosae disrupt barriers against the external environment, and the bactericidal actions of …

Neuropathy and ischaemia are two great pathologies of the diabetic foot which lead to the
characteristic features of foot ulceration (neuropathic and ischaemic) and Charcot …

Background and aims The study aimed at determining prevalence and risk factors (RFs) of
diabetic lower limb amputations (LLAs). Methods Electronic databases including PubMed …

Introduction: Chronic, nonhealing skin wounds claim> 3% of the health-care budget in
industrialized countries, and the incidence is rising. Currently, two parallel trends influence …

Background Studies on diabetic foot and its complications involving a significant and
representative sample of patients in South American countries are scarce. The main …

Diabetes Mellitus (DM) is known to have many complications. Diabetes and its
complications are rapidly becoming the world's most significant cause of morbidity and …

Objectives To develop and validate a model for predicting the risk of early diabetic foot ulcer
(DFU) based on systematic review and meta-analysis. Methods Data were analyzed from …

It is known that the relative importance of factors involved in the development of diabetic foot
problems can vary in both their presence and severity between patients and lesions. This …

Introduction Untreatable foot problems in diabetics may require lower extremity amputation,
which has a high level of patient mortality. This high mortality rate is worse than most …