Mapping epileptic activity: sources or networks for the clinicians?

F Pittau, P Mégevand, L Sheybani, E Abela… - Frontiers in …, 2014 - frontiersin.org
Epileptic seizures of focal origin are classically considered to arise from a focal
epileptogenic zone and then spread to other brain regions. This is a key concept for …

Electrical stimulation of the piriform cortex for the treatment of epilepsy: A review of the supporting evidence

JC Young, DN Vaughan, AG Paolini, GD Jackson - Epilepsy & behavior, 2018 - Elsevier
In this review, we consider how the piriform cortex is engaged in both focal and generalized
epilepsy networks and postulate the various neural pathways that can be effectively …

15q13. 3 homozygous knockout mouse model display epilepsy-, autism-and schizophrenia-related phenotypes

A Forsingdal, K Fejgin, V Nielsen, T Werge… - Translational …, 2016 - nature.com
Abstract The 15q13. 3 microdeletion syndrome is caused by a 1.5-MB hemizygous
microdeletion located on 15q13. 3 affecting seven genes: FAN1; MTMR10; TRPM1; miR …

Optogenetic activation of the reticular nucleus of the thalamus attenuates limbic seizures via inhibition of the midline thalamus

E Wicker, PA Forcelli - Epilepsia, 2021 - Wiley Online Library
Objective The nucleus reticularis of the thalamus (nRT) is most studied in epilepsy for its role
in the genesis of absence seizures; much less is known regarding its role in other seizure …

Altered intrathalamic GABAA neurotransmission in a mouse model of a human genetic absence epilepsy syndrome

C Zhou, L Ding, ME Deel, EA Ferrick, RB Emeson… - Neurobiology of …, 2015 - Elsevier
We previously demonstrated that heterozygous deletion of Gabra1, the mouse homolog of
the human absence epilepsy gene that encodes the GABA A receptor (GABA AR) α1 …

Cortical alterations in a model for absence epilepsy and febrile seizures: in vivo findings in mice carrying a human GABA (A) R gamma2 subunit mutation

J Witsch, D Golkowski, TTG Hahn, S Petrou… - Neurobiology of …, 2015 - Elsevier
Childhood absence epilepsy (CAE) is one of the most common forms of epilepsy among
children. The study of a large Australian family demonstrated that a point mutation in the …

Амигдала в системе регуляции репродуктивных функций организма при абсансной эпилепсии

ИИ Садртдинова, ЗР Хисматуллина - 2018 - elibrary.ru
В монографии изложены материалы по общей морфологии миндалевидного
комплекса и с помощью современного комплекса методов исследования дана оценка …

T-Type Calcium Channels in Epilepsy

AS Sack, TP Snutch - Voltage-Gated Calcium Channels, 2022 - Springer
Epilepsy is a complex neurological disorder commonly thought to involve hyperexcitable
neurons that recruit neuronal populations within circuits to generate aberrant synchronous …

Cav3.2 T‐type calcium channel mutation influences kindling‐induced thalamic neuronal firing patterns in Genetic Absence Epilepsy Rats From Strasbourg

N Çarçak, I Ali, K Powell, T Zheng, F Onat… - Epilepsia, 2019 - Wiley Online Library
Objective Recent data indicate that amygdala kindling leads to significant changes in
interictal neuronal firing patterns of thalamic reticular nucleus (TRN) neurons by decreasing …

Neuropeptide Y affects thalamic reticular nucleus neuronal firing and network synchronization associated with suppression of spike‐wave discharges

I Ali, A Gandrathi, T Zheng, MJ Morris, TJ O'Brien… - …, 2018 - Wiley Online Library
Summary Objectives Neuropeptide Y (NPY) potently suppresses spike‐wave discharges
(SWD s) in a genetic rat model of absence epilepsy (GAERS), but the underlying …