In this review, we consider how the piriform cortex is engaged in both focal and generalized epilepsy networks and postulate the various neural pathways that can be effectively …
A Forsingdal, K Fejgin, V Nielsen, T Werge… - Translational …, 2016 - nature.com
Abstract The 15q13. 3 microdeletion syndrome is caused by a 1.5-MB hemizygous microdeletion located on 15q13. 3 affecting seven genes: FAN1; MTMR10; TRPM1; miR …
E Wicker, PA Forcelli - Epilepsia, 2021 - Wiley Online Library
Objective The nucleus reticularis of the thalamus (nRT) is most studied in epilepsy for its role in the genesis of absence seizures; much less is known regarding its role in other seizure …
C Zhou, L Ding, ME Deel, EA Ferrick, RB Emeson… - Neurobiology of …, 2015 - Elsevier
We previously demonstrated that heterozygous deletion of Gabra1, the mouse homolog of the human absence epilepsy gene that encodes the GABA A receptor (GABA AR) α1 …
J Witsch, D Golkowski, TTG Hahn, S Petrou… - Neurobiology of …, 2015 - Elsevier
Childhood absence epilepsy (CAE) is one of the most common forms of epilepsy among children. The study of a large Australian family demonstrated that a point mutation in the …
Epilepsy is a complex neurological disorder commonly thought to involve hyperexcitable neurons that recruit neuronal populations within circuits to generate aberrant synchronous …
N Çarçak, I Ali, K Powell, T Zheng, F Onat… - Epilepsia, 2019 - Wiley Online Library
Objective Recent data indicate that amygdala kindling leads to significant changes in interictal neuronal firing patterns of thalamic reticular nucleus (TRN) neurons by decreasing …
Summary Objectives Neuropeptide Y (NPY) potently suppresses spike‐wave discharges (SWD s) in a genetic rat model of absence epilepsy (GAERS), but the underlying …