Ethnopharmacological relevance Xihuang pill as a famous traditional Chinese formula has
long been used as an adjuvant therapy for cancer. Aim of the study This study is aimed at …

Rationale: Gastric cancer (GC) is preceded by a stepwise progression of precancerous
gastric lesions. Distinguishing individuals with precancerous gastric lesions that have …

Rarely has a chemical elicited as much controversy as dichloroacetate (DCA). DCA was
initially considered a dangerous toxic industrial waste product, then a potential treatment for …

This study investigated the chemotherapeutic effects of 5‐fluorouracil (5‐FU), metformin
(Met), and/or thymoquinone (TQ) single/dual/triple therapies in the HT29, SW480 and …

Colorectal cancer is the third most frequently encountered cancer worldwide. While current
chemotherapeutics help to manage the disease to some extent, they have eluded achieving …

Objective: Colorectal cancer is severely challenging because of the insufficient
understanding of the mechanism underlying its resistance to clinical chemotherapy. The …

The discovery of drug compounds has a long history in drug repurposing, notably by
fortuitous findings. It has taken a new path in the creation of novel therapeutics based on …

Phaeurus antarcticus is a member of the Desmarestiaceae family endemic to the Antarctic
Peninsula. Reports addressing its chemical composition and biological activities are scarce …

Colorectal cancer (CRC) patients have been shown to possess an altered gut microbiome.
Diet is a well-established modulator of the microbiome, and thus, dietary interventions might …

Often, in traditional laboratory courses, students carry out “experiments” for which the results
are already known, following protocols that they are expected to perform as written. Using …