Oxidative stress and vascular dysfunction in the retina: Therapeutic strategies

Y Ruan, S Jiang, A Musayeva, A Gericke - Antioxidants, 2020 - mdpi.com
Many retinal diseases, such as diabetic retinopathy, glaucoma, and age-related macular
(AMD) degeneration, are associated with elevated reactive oxygen species (ROS) levels …

Inherited retinal dystrophies: role of oxidative stress and inflammation in their physiopathology and therapeutic implications

I Pinilla, V Maneu, L Campello, L Fernández-Sánchez… - Antioxidants, 2022 - mdpi.com
Inherited retinal dystrophies (IRDs) are a large group of genetically and clinically
heterogeneous diseases characterized by the progressive degeneration of the retina …

Apoptotic effect of organophosphorus insecticide chlorpyrifos on mouse retina in vivo via oxidative stress and protection of combination of vitamins C and E

F Yu, Z Wang, B Ju, Y Wang, J Wang, D Bai - Experimental and Toxicologic …, 2008 - Elsevier
Organophosphorus insecticide poisoning is widely investigated, and a growing number of
evidence indicates its effects to cause ocular lesions, but the mechanisms of its ocular …

The potential role of amyloid β in the pathogenesis of age-related macular degeneration

T Yoshida, K Ohno-Matsui, S Ichinose… - The Journal of …, 2005 - Am Soc Clin Investig
Drusen are extracellular deposits that lie beneath the retinal pigment epithelium (RPE) and
are the earliest signs of age-related macular degeneration (AMD). Recent proteome …

Good bacteria, oxidative stress and neurological disorders: Possible therapeutical considerations

M Soheili, A Alinaghipour, M Salami - Life sciences, 2022 - Elsevier
Although oxidative agents such as free radicals can fight pathogens, an imbalance of
oxidant/anti-oxidant activity can lead to harmful effects in our body known as oxidative …

Antioxidants and neurodegenerative eye disease

Y Semenova, G Bjørklund - Critical Reviews in Food Science and …, 2024 - Taylor & Francis
Neurodegenerative ocular disorders mostly develop with aging and present great
complications in the quality of life. Glaucoma and age-related macular degeneration …

Antioxidant supplementation lowers exercise‐induced oxidative stress in young overweight adults

HK Vincent, CM Bourguignon, KR Vincent… - …, 2006 - Wiley Online Library
Objective: To determine whether antioxidant (AOX) supplementation attenuates post‐
exercise oxidative stress and contributors to oxidative stress (inflammation, blood lipids) in …

Pomegranate protective effect on experimental ischemia/reperfusion retinal injury in rats (histological and biochemical study)

HE Hashem, MR Abd El-Haleem, MG Amer… - Ultrastructural …, 2017 - Taylor & Francis
Oxidative stress is one mechanism involved in the pathogenesis of ischemia/reperfusion (/R)
retinal injury. The histological, biochemical, and functional changes associated with …

Retinal pathology is associated with increased blood–retina barrier permeability in a diabetic and hypercholesterolaemic pig model: Beneficial effects of the LpPLA2 …

NK Acharya, X Qi, EL Goldwaser… - Diabetes and …, 2017 - journals.sagepub.com
Using a porcine model of diabetes mellitus and hypercholesterolaemia, we previously
showed that diabetes mellitus and hypercholesterolaemia is associated with a chronic …

Association of vitreous vitamin C depletion with diabetic macular ischemia in proliferative diabetic retinopathy

SW Park, W Ghim, S Oh, Y Kim, UC Park, J Kang… - PLoS …, 2019 - journals.plos.org
Purpose Vitreous vitamin C, as an anti-oxidant, is responsible for regulating oxygen tension
and oxidative stress in the eye. Oxidative stress and retinal ischemia are implicated in the …