DHCR7 promotes tumorigenesis via activating PI3K/AKT/mTOR signalling pathway in bladder cancer
Y Li, Y Zhou, M Huang, Z Wang, D Liu, J Liu, X Fu… - Cellular signalling, 2023 - Elsevier
Bladder cancer (BCa) is a common malignancy with uncertain molecular mechanism. 7-
dehydrocholesterol reductase (DHCR7), the enzyme of mammalian sterol biosynthesis …
dehydrocholesterol reductase (DHCR7), the enzyme of mammalian sterol biosynthesis …
Roles of non-coding RNAs in the metabolism and pathogenesis of bladder cancer
DRA Sanya, D Onésime - Human Cell, 2023 - Springer
Bladder cancer (BC) is featured as the second most common malignancy of the urinary tract
worldwide with few treatments leading to high incidence and mortality. It stayed a virtually …
worldwide with few treatments leading to high incidence and mortality. It stayed a virtually …
GREM1 is a potential biomarker for the progression and prognosis of bladder cancer
P Jiang, L Xu, J Ning, F Cheng - World Journal of Surgical Oncology, 2023 - Springer
Abstract Background Gremlin-1 (GREM1) is a protein closely related to tumor growth,
although its function in bladder cancer (BCa) is currently unknown. Our first objective was to …
although its function in bladder cancer (BCa) is currently unknown. Our first objective was to …
Small RNA-sequencing reveals the involvement of microRNA-132 in benzo [a] pyrene-induced toxicity in primary human blood cells
R Souki, J Amosse, V Genêt, M Le Gall… - Environmental …, 2023 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) are widely distributed environmental
contaminants, triggering deleterious effects such as carcinogenicity and …
contaminants, triggering deleterious effects such as carcinogenicity and …
Exposure to environmental pollutants and genetic variants related to oxidative stress and xenobiotic metabolism—Association with prostate cancer
B Álvarez-González, AF Hernández… - Environmental …, 2024 - Elsevier
This study assessed whether genetic variants coding for certain enzymes involved in
xenobiotic detoxification, antioxidant defences and DNA repair, along with exposure to …
xenobiotic detoxification, antioxidant defences and DNA repair, along with exposure to …
Association Study between Antioxidant Nutrient Intake and Low Bone Mineral Density with Oxidative Stress-Single Nucleotide Variants: GPX1 (rs1050450 and …
RF Jiménez-Ortega, DI Aparicio-Bautista… - Antioxidants, 2023 - mdpi.com
Oxidative stress is essential in developing multiple bone metabolism diseases, including
osteoporosis. Single-nucleotide variants (SNVs) have been associated with oxidative stress …
osteoporosis. Single-nucleotide variants (SNVs) have been associated with oxidative stress …
Network pharmacology-integrated molecular docking analysis of phytocompounds of Caesalpinia pulcherrima (peacock flower) as potential anti-metastatic agents
T Hao Dong, A Yau Wen Ning… - Journal of Biomolecular …, 2024 - Taylor & Francis
Caesalpinia pulcherrima, or peacock flower, has been a subject of cancer therapeutics
research, showing promising anti-cancer and anti-metastatic properties. The present …
research, showing promising anti-cancer and anti-metastatic properties. The present …
Polymorphisms of antioxidant enzymes SOD2 (rs4880) and GPX1 (rs1050450) are associated with bladder cancer risk or its aggressiveness
Background and Objectives: Oxidative stress induced by increased reactive oxygen species
(ROS) production plays an important role in carcinogenesis. The entire urinary tract is …
(ROS) production plays an important role in carcinogenesis. The entire urinary tract is …
The Role of Emodin in the Treatment of Bladder Cancer Based on Network Pharmacology and Experimental Verification
F Liu, J Li, B Zhou, Y Shen, J Tang… - … Chemistry & High …, 2024 - ingentaconnect.com
Background and Purpose: Emodin, a compound derived from rhubarb and various
traditional Chinese medicines, exhibits a range of pharmacological actions, including …
traditional Chinese medicines, exhibits a range of pharmacological actions, including …