The study of homologous recombination has its historical roots in meiosis. In this context,
recombination occurs as a programmed event that culminates in the formation of crossovers …

Meiosis, the mechanism of creating haploid gametes, is a complex cellular process
observed across sexually reproducing organisms. Fundamental to meiosis is the process of …

The synaptonemal complex is a tripartite proteinaceous ultrastructure that forms between
homologous chromosomes during prophase I of meiosis in the majority of eukaryotes. It is …

Meiosis is the cell division that reshuffles genetic information between generations.
Recently, much progress has been made in understanding this process; in particular, the …

Meiosis halves diploid chromosome numbers to haploid levels that are essential for sexual
reproduction in most eukaryotes. Meiotic recombination ensures the formation of bivalents …

FANCM suppresses crossovers in plants by unwinding recombination intermediates. In
wheat, crossovers are skewed toward the chromosome ends, thus limiting generation of …

The number of meiotic crossovers (COs) is tightly regulated within a narrow range, despite a
large excess of molecular precursors. The factors that limit COs remain largely unknown …

At the final step of homologous recombination, Holliday junction-containing joint molecules
(JMs) are resolved to form crossover or noncrossover products. The enzymes responsible …

Meiosis is a specialized cell division, essential in most reproducing organisms to halve the
number of chromosomes, thereby enabling the restoration of ploidy levels during …

During meiosis, homologous chromosomes undergo crossover recombination, which is
typically concentrated in narrow hot spots that are controlled by genetic and epigenetic …