Ferroptosis in cancer and cancer immunotherapy

L Zhao, X Zhou, F Xie, L Zhang, H Yan… - Cancer …, 2022 - Wiley Online Library
The hallmark of tumorigenesis is the successful circumvention of cell death regulation for
achieving unlimited replication and immortality. Ferroptosis is a newly identified type of cell …

Lifestyle, oxidative stress, and antioxidants: back and forth in the pathophysiology of chronic diseases

M Sharifi-Rad, NV Anil Kumar, P Zucca… - Frontiers in …, 2020 - frontiersin.org
Oxidative stress plays an essential role in the pathogenesis of chronic diseases such as
cardiovascular diseases, diabetes, neurodegenerative diseases, and cancer. Long term …

A click chemistry-mediated all-peptide cell printing hydrogel platform for diabetic wound healing

J Huang, R Yang, J Jiao, Z Li, P Wang, Y Liu… - Nature …, 2023 - nature.com
High glucose-induced vascular endothelial injury is a major pathological factor involved in
non-healing diabetic wounds. To interrupt this pathological process, we design an all …

Ferroptosis in cancer cell biology

CM Bebber, F Müller, L Prieto Clemente, J Weber… - Cancers, 2020 - mdpi.com
A major hallmark of cancer is successful evasion of regulated forms of cell death. Ferroptosis
is a recently discovered type of regulated necrosis which, unlike apoptosis or necroptosis, is …

Overview of the antioxidant and anti-inflammatory activities of selected plant compounds and their metal ions complexes

P Mucha, A Skoczyńska, M Małecka, P Hikisz… - Molecules, 2021 - mdpi.com
Numerous plant compounds and their metal-ion complexes exert antioxidative, anti-
inflammatory, anticancer, and other beneficial effects. This review highlights the different …

Nanozyme‐enabled treatment of cardio‐and cerebrovascular diseases

Y Zhang, W Liu, X Wang, Y Liu, H Wei - Small, 2023 - Wiley Online Library
Cardio‐and cerebrovascular diseases are two major vascular‐related diseases that lead to
death worldwide. Reactive oxygen species (ROS) play a vital role in the occurrence and …

The crosstalk between the gut microbiota and mitochondria during exercise

A Clark, N Mach - Frontiers in physiology, 2017 - frontiersin.org
Many physiological changes occur in response to endurance exercise in order to adapt to
the increasing energy needs, mitochondria biogenesis, increased reactive oxygen species …

Prohibitins: a critical role in mitochondrial functions and implication in diseases

A Signorile, G Sgaramella, F Bellomo, D De Rasmo - Cells, 2019 - mdpi.com
Prohibitin 1 (PHB1) and prohibitin 2 (PHB2) are proteins that are ubiquitously expressed,
and are present in the nucleus, cytosol, and mitochondria. Depending on the cellular …

Resveratrol and brain mitochondria: a review

FR Jardim, FT de Rossi, MX Nascimento… - Molecular …, 2018 - Springer
Abstract Resveratrol (3, 4', 5-trihydroxystilbene; C 14 H 12 O 3) is a polyphenolic phytoalexin
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …

Metabolic heterogeneity of cancer cells: an interplay between HIF-1, GLUTs, and AMPK

NT Moldogazieva, IM Mokhosoev, AA Terentiev - Cancers, 2020 - mdpi.com
It has been long recognized that cancer cells reprogram their metabolism under hypoxia
conditions due to a shift from oxidative phosphorylation (OXPHOS) to glycolysis in order to …