[PDF][PDF] Acute liver failure: summary of a workshop

WM Lee, RH Squires Jr, SL Nyberg, E Doo… - …, 2008 - Wiley Online Library
Acute liver failure (ALF) is a rare but challenging clinical syndrome with multiple causes; a
specific etiology cannot be identified in 15% of adult and 50% of pediatric cases. The course …

Evaluating drug efficacy and toxicology in three dimensions: using synthetic extracellular matrices in drug discovery

GD Prestwich - Accounts of chemical research, 2008 - ACS Publications
The acceptance of the new paradigm of 3-D cell culture is currently constrained by the lack
of a biocompatible material in the marketplace that offers ease of use, experimental …

Photocrosslinkable hyaluronan-gelatin hydrogels for two-step bioprinting

A Skardal, J Zhang, L McCoard, X Xu… - … Engineering Part A, 2010 - liebertpub.com
Bioprinting by the codeposition of cells and biomaterials is constrained by the availability of
printable materials. Herein we describe a novel macromonomer, a new two-step …

Hyaluronan/collagen hydrogels containing sulfated hyaluronan improve wound healing by sustained release of heparin-binding EGF-like growth factor

S Thönes, S Rother, T Wippold, J Blaszkiewicz… - Acta biomaterialia, 2019 - Elsevier
Functional biomaterials that are able to bind, stabilize and release bioactive proteins in a
defined manner are required for the controlled delivery of such to the desired place of action …

Heparin-regulated release of growth factors in vitro and angiogenic response in vivo to implanted hyaluronan hydrogels containing VEGF and bFGF

DB Pike, S Cai, KR Pomraning, MA Firpo, RJ Fisher… - Biomaterials, 2006 - Elsevier
Controlled release of human vascular endothelial growth factor (VEGF) or basic fibroblast
growth factor (bFGF) from hydrogels composed of chemically modified hyaluronan (HA) and …

Rheological properties of cross‐linked hyaluronan–gelatin hydrogels for tissue engineering

JL Vanderhooft, M Alcoutlabi, JJ Magda… - Macromolecular …, 2009 - Wiley Online Library
Hydrogels that mimic the natural extracellular matrix (ECM) are used in three‐dimensional
cell culture, cell therapy, and tissue engineering. A semi‐synthetic ECM based on cross …

Osteochondral Defect Repair with Autologous Bone Marrow–Derived Mesenchymal Stem Cells in an Injectable, In Situ, Cross-Linked Synthetic Extracellular Matrix

Y Liu, XZ Shu, GD Prestwich - Tissue engineering, 2006 - liebertpub.com
A co-cross-linked synthetic extracellular matrix (sECM) composed of chemically modified
hyaluronic acid and gelatin was used as a cell delivery vehicle for osteochondral defect …

Encapsulation and 3D culture of human adipose-derived stem cells in an in-situ crosslinked hybrid hydrogel composed of PEG-based hyperbranched copolymer and …

W Hassan, Y Dong, W Wang - Stem cell research & therapy, 2013 - Springer
Introduction Cell therapy using adipose-derived stem cells has been reported to improve
chronic wounds via differentiation and paracrine effects. One such strategy is to deliver stem …

Synthesis and evaluation of injectable, in situ crosslinkable synthetic extracellular matrices for tissue engineering

XZ Shu, S Ahmad, Y Liu… - Journal of biomedical …, 2006 - Wiley Online Library
Simple and effective biocompatible materials that mimic the natural extracellular matrix
(ECM) were developed for a variety of uses in regenerative medicine. These synthetic ECMs …

Release of basic fibroblast growth factor from a crosslinked glycosaminoglycan hydrogel promotes wound healing

Y Liu, S Cai, XZ Shu, J Shelby… - Wound repair and …, 2007 - Wiley Online Library
We describe synthetic extracellular matrix (sECM) hydrogel films composed of co‐
crosslinked thiolated derivatives of chondroitin 6‐sulfate (CS) and heparin (HP) for …