G protein-coupled receptor kinases (GRKs) are emerging as important integrative nodes in
cell migration processes. Recent evidence links GRKs (particularly the GRK2 isoform) to the …

G-protein-coupled receptor kinases (GRKs) are serine/threonine protein kinases originally
discovered for their role in G-protein-coupled receptor (GPCR) phosphorylation. Recent …

In addition to oncogenic drivers, signaling nodes can critically modulate cancer-related
cellular networks to strength tumor hallmarks. We identify G-protein-coupled receptor kinase …

T cell infiltration to synovial tissue is an early pathogenic mechanism of rheumatoid arthritis
(RA). In the present work, we reveal that G protein coupled receptor kinase 2 (GRK2) is …

DNA repair promotes the progression and recurrence of glioblastoma (GBM). However,
there remain no effective therapies for targeting the DNA damage response and repair …

Abstract Phosphatidylethanolamine-binding protein 1 (PEBP1), a small 21 kDa protein, is
implicated in several key processes of the living cell. The deregulation of PEBP1, especially …

G protein-coupled receptor kinases (GRKs) are protein kinases that function in concert with
arrestins in the regulation of a diverse class of G protein-coupled receptors (GPCRs) …

The new horizon for cardiac therapy may lie beneath the surface, with the downstream
mediators of G protein–coupled receptor (GPCR) activity. Targeted approaches have shown …

G protein-coupled receptor kinases (GRKs) are classically known for their role in regulating
the activity of the largest known class of membrane receptors, which influence diverse …

G protein-coupled receptor kinases (GRKs) are serine/threonine kinases that regulate a
large and diverse class of G protein-coupled receptors (GPCRs). Through GRK …