Introducing the role of genotoxicity in neurodegenerative diseases and neuropsychiatric disorders

GE Kisby, DM Wilson III, PS Spencer - International journal of molecular …, 2024 - mdpi.com
Decades of research have identified genetic and environmental factors involved in age-
related neurodegenerative diseases and, to a lesser extent, neuropsychiatric disorders …

The tryptophan catabolite or kynurenine pathway in autism spectrum disorder; a systematic review and meta‐analysis

AF Almulla, Y Thipakorn, C Tunvirachaisakul… - Autism …, 2023 - Wiley Online Library
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
impaired social communication and interaction, as well as rigid and unchanging interests …

[HTML][HTML] Investigating brain–gut microbiota dynamics and inflammatory processes in an autistic-like rat model using MRI biomarkers during childhood and …

L Palanivelu, YY Chen, CJ Chang, YW Liang… - Neuroimage, 2024 - Elsevier
Autism spectrum disorder (ASD) is characterized by social interaction deficits and repetitive
behaviors. Recent research has linked that gut dysbiosis may contribute to ASD-like …

Gene association classification for autism spectrum disorder: Leveraging gene embedding and differential gene expression profiles to identify disease-related genes

A Suratanee, K Plaimas - Applied Sciences, 2023 - mdpi.com
Identifying genes associated with autism spectrum disorder (ASD) is crucial for
understanding the underlying mechanisms of the disorder. However, ASD is a complex …

Correlation of biochemical markers and inflammatory cytokines in autism spectrum disorder (ASD)

AS Noori, P Rajabi, J Sargolzaei, A Alaghmand - BMC pediatrics, 2024 - Springer
Abstract Introduction Autism Spectrum Disorder (ASD) is a disorder that severely affects
neurodevelopment, and its underlying causes are not yet entirely understood. Research …

Ultrarare Variants in DNA Damage Repair Genes in Pediatric Acute-Onset Neuropsychiatric Syndrome or Acute Behavioral Regression in Neurodevelopmental …

JL Cunningham, J Frankovich, RA Dubin… - Developmental …, 2024 - karger.com
Acute onset of severe psychiatric symptoms or regression may occur in children with
premorbid neurodevelopmental disorders, although typically developing children can also …

Autism spectrum disorder: Pathogenesis, biomarker, and intervention therapy

H Zhuang, Z Liang, G Ma, A Qureshi, X Ran… - MedComm, 2024 - Wiley Online Library
Autism spectrum disorder (ASD) has become a common neurodevelopmental disorder. The
heterogeneity of ASD poses great challenges for its research and clinical translation. On the …

Integrated gene expression and alternative splicing analysis in human and mouse models of Rett syndrome

S Gioiosa, S Gasparini, C Presutti, A Rinaldi… - Scientific Reports, 2025 - nature.com
Mutations of the MECP2 gene lead to Rett syndrome (RTT), a rare developmental disease
causing severe intellectual and physical disability. How the loss or defective function of …

[HTML][HTML] The mast cells-Cytokines axis in Autism Spectrum Disorder

E Kovacheva, M Gevezova, M Maes, V Sarafian - Neuropharmacology, 2024 - Elsevier
Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disturbance, diagnosed
in early childhood. It is associated with varying degrees of dysfunctional communication and …

The relationship between neurodevelopmental transcriptional programs and insomnia: From Rubinstein-Taybi syndrome into energy metabolism

L Cunha, M Paschalidis, M Moysés-Oliveira… - Sleep Medicine, 2023 - Elsevier
Neurodevelopmental disorders (NDD) are characterized by cognitive, emotional, and/or
motor skills impairment since childhood, and sleep disturbances are a common comorbidity …