Lipid polymer hybrid nanoparticles: a custom-tailored next-generation approach for cancer therapeutics

KR Gajbhiye, R Salve, M Narwade, A Sheikh… - Molecular Cancer, 2023 - Springer
Lipid-based polymeric nanoparticles are the highly popular carrier systems for cancer drug
therapy. But presently, detailed investigations have revealed their flaws as drug delivery …

Recent advances in intranasal liposomes for drug, gene, and vaccine delivery

VA Duong, TTL Nguyen, HJ Maeng - Pharmaceutics, 2023 - mdpi.com
Liposomes are safe, biocompatible, and biodegradable spherical nanosized vesicles
produced from cholesterol and phospholipids. Recently, liposomes have been widely …

Coating materials to increase the stability of liposomes

D Pasarin, AI Ghizdareanu, CE Enascuta, CB Matei… - Polymers, 2023 - mdpi.com
Liposomes carry various compounds with applications in pharmaceutical, food, and
cosmetic fields, and the administration route is especially parenteral, oral, or transdermal …

Anti-angiogenic carbon nanovesicles loaded with bevacizumab for the treatment of age-related macular degeneration

A Anand, HJ Jian, HH Huang, LE Hean, YJ Li, JY Lai… - Carbon, 2023 - Elsevier
Intraocular angiogenesis mediated by vascular endothelial growth factor (VEGF) and the
related ocular disease, age-related macular degeneration (AMD), is the leading cause of …

Biomimetic nanovesicles—sources, design, production methods, and applications

MF Mougenot, VS Pereira, ALR Costa, M Lancellotti… - Pharmaceutics, 2022 - mdpi.com
Despite all the progress in the field of liposomes and nanoparticles for applications as drug
and gene delivery systems, the specific targeting and immune system escape capabilities of …

Understanding the journey of biopolymeric nanoformulations for oral drug delivery: Conventional to advanced treatment approaches

A Sharma, N Jangra, D Dheer, SK Jha, G Gupta… - European Polymer …, 2024 - Elsevier
The oral route of drug administration offers a convenient, cost-efficient, and non-invasive
means of administering medications. Nevertheless, as newly developed active …

[HTML][HTML] Solubilization techniques used for poorly water-soluble drugs

B Xie, Y Liu, X Li, P Yang, W He - Acta Pharmaceutica Sinica B, 2024 - Elsevier
Currently, about 40% of approved drugs and nearly 90% of drug candidates are poorly
water-soluble drugs. Low solubility reduces the likelihood that these drugs can be effectively …

Nano-drug delivery systems in oral cancer therapy: recent developments and prospective

Y Zhang, Y Wu, H Du, Z Li, X Bai, Y Wu, H Li, M Zhou… - Pharmaceutics, 2023 - mdpi.com
Oral cancer (OC), characterized by malignant tumors in the mouth, is one of the most
prevalent malignancies worldwide. Chemotherapy is a commonly used treatment for OC; …

Biopolymer-and lipid-based carriers for the delivery of plant-based ingredients

L Gali, A Pirozzi, F Donsì - Pharmaceutics, 2023 - mdpi.com
Natural ingredients are gaining increasing attention from manufacturers following
consumers' concerns about the excessive use of synthetic ingredients. However, the use of …

Oxime therapy for brain AChE reactivation and neuroprotection after organophosphate poisoning

DA Kuznetsova, GA Gaynanova, EA Vasilieva… - Pharmaceutics, 2022 - mdpi.com
One of the main problems in the treatment of poisoning with organophosphorus (OPs)
inhibitors of acetylcholinesterase (AChE) is low ability of existing reactivators of AChE that …